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Common Low-Density Lipoprotein Receptor p.G116S Variant Has a Large Effect on Plasma Low-Density Lipoprotein Cholesterol in Circumpolar Inuit Populations
Download2014-11-20
Dubé, Joseph B., Wang, Jian, Cao, Henian, McIntyre, Adam D., Johansen, Christopher T., Hopkins, Scarlett E., Stringer, Randa, Hosseinzadeh, Siyavash, Kennedy, Brooke A., Ban, Matthew R., Young, T. Kue, Connelly, Philip W., Dewailly, Eric, Bjerregaard, Peter, Boyer, Bert B., Hegele, Robert A.
"Background: Inuit are considered to be vulnerable to cardiovascular disease because their lifestyles are becoming more Westernized. During sequence analysis of Inuit individuals at extremes of lipid traits, we identified 2 nonsynonymous variants in low-density lipoprotein receptor (LDLR), namely...
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Contributions to chronic disease prevention and control: studies among the Kivalliq Inuit since 1990
Download2003-12-01
"A population-based health interview and examination survey of 8 Inuit communities in the Kivalliq region of Nunavut, Canada, during the early 1990s has resulted in an increased understanding of the burden and extent of cardiovascular diseases and diabetes and their risk factors such as genetics,...
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2012
McCarthy, G., Crichton, N.J., Linck, T., Seers, K., Titchen, A., Kitson, A., Edwards, R.T., Wallin, L., Hawkes, C., Estabrooks, C.A., Mockford, C., Cox, K., Harvey, G., Eldh, A.C., McCormack, B., Rycroft-Malone, G.
Background: Research evidence underpins best practice, but is not always used in healthcare. The Promoting Action on Research Implementation in Health Services (PARIHS) framework suggests that the nature of evidence, the context in which it is used, and whether those trying to use evidence are...
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Innovative strategic Canadian research training from TomorrOw’s Research Cardiovascular Health Care Professionals (TORCH).
Download2004
Lopaschuk, G., Ezekowitz, C., Armstrong, P.W., Michelakis, E., Seldon, R., Ghali, W.A., Archer, S., Anderson, T., Jensen, L., Hayward, R.
Cardiovascular research training is experiential, and \"skills\" are traditionally acquired through a master-apprentice paradigm. The complexity of contemporary clinical research requires a new model for research training. Facilitated through a Strategic Training Program Initiative, the Canadian...
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Knowledge and understanding of urinary incontinence: Survey of family practitioners in northern Alberta.
Download2013
Wagg, A., Hunter, K. F., Nguyen, K.
OBJECTIVE: To investigate family physicians' knowledge of, attitudes toward, and understanding of urinary incontinence (UI), as well as their perceptions of barriers to continence care, as a foundation for designing interventions to improve service provision for those in northern Alberta who...
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Social-interaction knowledge translation for in-home management of urinary incontinence and chronic care.
Download2013
Forbes, D., Jansen, L., Forchuk, C., McWilliam, C.
Although urinary incontinence (UI) can be managed conservatively, it is a principal reason for the breakdown of in-home family care. This study explored the social interaction processes of knowledge translation (KT) related to how UI management knowledge might be translated within in-home care....