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Skip to Search Results- 1Abdelfattah, Ahmed
- 1Alford, Spencer Caleb
- 1Belal, Ahmed S. F.
- 1Carlson, Haley J
- 1Fraser, Alastair
- 1Ghoraishi Kahangi, Maryam Sadat
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Directed Evolution Approaches for Improved Genetically Encoded Fluorescent Calcium Ion and Voltage Indicators
DownloadFall 2014
Fluorescent proteins (FP) have revolutionized our imaging technologies and facilitated visualization of biochemical and physiological processes occurring in complex biological systems, which has opened up a new and unprecedented era in cell biology. Although FPs mainly serve as passive...
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Fall 2015
The expansion of the fluorescent protein (FP) colour palette through discovery of more species possessing FPs and by subjecting them to intensive protein engineering efforts has greatly aided the effectiveness of FP-based biosensor designs. Currently, the main FP-based methods for detecting...
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Expanding the optogenetic toolkit with a photocleavable protein and a near infrared pH indicator
DownloadFall 2017
Optogenetics is an emerging biological technique that is causing a revolution in life science. It uses optical methods to control and visualize genetically targeted biological events in a relatively non-invasive and spatiotemporally precise manner. Optogenetics requires advanced optical...
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Spring 2010
The procedure for milling micrometre scale cantilevers of lutetium iron garnet using a focused ion beam microscope was developed. The infrastructure to study these cantilevers using rotational hysteresis loops and ferromagnetic resonance experiments was set up. The cantilevers were shown to...
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Investigation on the uptake of functional proteins and infectious prions into wheat plants through the root system
DownloadSpring 2014
Prions are the proteinaceous particle responsible for infections in a class of neurodegenerative diseases. These diseases affect a number of mammals including cervids where it is termed Chronic Wasting Disease (CWD). Prions enter the environment and persist for years. Plants have the ability to...
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Nanophotonic detection of nanomechanical structures for use toward mass sensing applications
DownloadSpring 2014
Nanomechanical beam resonators show much promise for use in integrated on-chip mass sensing systems. This follows from their own very small masses and also their ability to store the mechanical energy of their oscillations to produce strong measurable mechanical response signals. To achieve...
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Spring 2011
Intracellular pH was monitored at the cytosolic surface of plasma membrane solute transporters (Na+/H+/nucleoside co-transporters, or Cl-/HCO3- exchangers), using pH-sensitive fluorescent proteins (FPs), dual emission green FP (deGFP4) and a monomeric red FP Nectarine (mNect), whose development...
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Fall 2018
Ghoraishi Kahangi, Maryam Sadat
Due to their ability to measure extremely small displacements and forces, nanomechanical cantilevers have attracted considerable attention from numerous scientific communities, each exploring a variety of applications. Though typically operated in either vacuum or air, operation of the device in...