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Development of Polymeric Micelles for Site Specific Delivery of Nonsteroidal Anti-Inflammatory Drugs: Effect on the Cardiovascular Risk in an Experimental Model of Arthritis
DownloadFall 2019
Non-steroidal anti-inflammatory drugs (NSAIDs), which inhibit cyclooxygenase (COX) enzymes, are among the most widely used medications worldwide with proven efficacy in controlling inflammation and pain associated various disease conditions. The chronic systemic use of most NSAIDs, however, is...
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Gelled and Foamed Microemulsion-based Systems for Cutaneous Drug Delivery of Diclofenac Sodium
DownloadFall 2017
Abstract Topical formulations of diclofenac have become popular for treating various painful inflammatory conditions. Yet, not all formulations are suitable candidates for dermal delivery as the skin acts as a natural barrier that limits drug penetration. This barrier challenges the efficacy of...
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