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Skip to Search Results- 47Graduate and Postdoctoral Studies (GPS), Faculty of
- 47Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 8Biological Sciences, Department of
- 5Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 3Biological Sciences, Department of/Other Publications (Biological Sciences)
- 2Roy Berg Kinsella Research Ranch
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Fall 2013
Glomus cells of the carotid body are peripheral chemoreceptors that detect changes in arterial oxygen levels. Hypoxia suppresses oxygen-sensitive K+ channels in glomus cells, resulting in cytosolic Ca2+ ([Ca2+]i) elevation in glomus cells via the activation of voltage-gated Ca2+ channels. The...
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Regulation of Cardiac Gap Junctional Communication: Metabolic regulation of Cx40 and Cx43 via phosphorylation
DownloadFall 2015
Alterations in myocardial metabolism and cardiac electrophysiology associated with structural heart disease generate lethal arrhythmias. Differential levels of energy (ATP) supply and demand are generated with structural heart disease that is expected to activate 5’-amp activated protein kinase...
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2008
O'Sullivan, N.P., Wong, G.K., Lawley, C.T., McKay, J.C., Groenen, M.A., Fulton, J.E., Crooijmans, R.P., Muir, W.M., Megens, H.J., Cheng, H.H., McLeod, S., Zhang, H.M., Zhang, Y., Albers, G.A.A., Delany, M.E., Settar, P., Okimoto, R., Vereijken, A., Wang, J., Jungerius-Rattink, A.
In 2004 the chicken genome sequence and more than 2.8 million single nucleotide polymorphisms (SNPs) were reported. This information greatly enhanced the ability of poultry scientists to understand chicken biology, especially with respect to identification of quantitative trait loci (QTL) and...
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Fall 2023
Sleep is a vital neurobiological process, yet despite its fundamental significance, delineating the endogenous neural pathways involved has been slow to progress due to a lack of diverse sleep models. Anesthesia, which has direct behavioural parallels to natural sleep, and which is often linked...
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Spring 2011
Large corporations have a significant amount of working capital tied into the acquisition and storage of spare parts. In the industry, spare parts inventory policies and strategies are often developed in isolation from reliability centered maintenance practices – this results in significant...
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1988-01-01
Zarain-Herzberg, A., Fliegel, Larry, MacLennan, D. H.
We have isolated two overlapping 17-kilobase (kb) genomic clones which, together, encode the rabbit fasttwitch skeletal muscle calsequestrin. The calsequestrin gene is 8.6 kb in length and consists of 11 exons. Sl nuclease protection and primer extension analyses position the transcription...
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The Effect of Caffeine on the Neurobehavioral and Neuropathological Outcome of the Newborn Rat
DownloadSpring 2010
Caffeine is used for the treatment of apnea of prematurity. The objective of this study was to determine the long term neuropathological and neurobehavioral effects of caffeine on the immature rat brain. Newborn rats were injected with either caffeine, or normal saline from postnatal days 3 to 7,...
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The effect of long-term interleukin-1 beta exposure on sensory neuron electrical membrane properties: implications for neuropathic pain
DownloadSpring 2011
The effect of interleukin-1 beta (IL-1β) on the electrical properties of sensory neurons was assessed at comparable levels and exposure times to those found in animal models of neuropathic pain. Experiments involved whole cell current- or voltage-clamp recordings from rat dorsal root ganglion...