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Skip to Search Results- 1Abdelrahman, Ali Satti Abdellatif
- 1Araya, Luam Ellen
- 1Bak, Jessi J.
- 1Beck, Elizabeth M
- 1Blunt, Brian
- 1Brandon, Jordan T
- 2Gamal El-Din, Mohamed (Civil and Environmental Engineering)
- 2Overduin, Michael (Biochemistry)
- 1Ballermann, Barbara (Medicine)
- 1Belosevic, Miodrag (Biological Sciences)
- 1Gammal El-Din, Mohamed (Department of Civil and Environmental Engineering)/Miodrag, Belosevic (Department of Biological Sciences)
- 1Hwang, Peter (Biochemistry)
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Genotoxicity and Mutagenicity of Extractable Organics from Oil Sands Process-Affected Water
DownloadFall 2015
Oil sands process-affected water (OSPW) is produced in the surface mining industry during the hot-water extraction of bitumen from oil-sands ore. Its acid extractable organic (AEO) fraction is known to be acutely toxic, but few studies have addressed its genotoxicity or mutagenicity. Here, the in...
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Fall 2021
Caspases are a family of enzymes that regulate biological processes, such as inflammation and programmed cell death, through proteolysis. For example, in the intrinsic pathway of apoptosis, cell death signaling involves cytochrome c release from the mitochondria, which leads to the activation of...
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Monitoring Macrophage Immune Gene Expression Profiles as an Early Indicator System for Examining the Bioactivity of Oil Sands Process Affected Waters
DownloadFall 2021
Oil sands process-affected waters (OSPW) are by-products of bitumen (i.e. oil) extraction from the oil sands located in northern Alberta. These large volumes of water are held in tailings ponds and cannot be released due to their potential toxic effects. Overall, tailings ponds and mining...
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Pyranopterin Coordination Controls Molybdenum Electrochemistry in Escherichia coli Nitrate Reductase
DownloadFall 2015
Molybdenum is an essential trace element for most species on the earth. Molybdoenzymes (enzymes containing Molybdenum) play diverse roles in human health, global geochemical cycles, and bacterial metabolism. Interestingly, nitrate reductase (NarGHI) isolated from the common gut bacterium...
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Fall 2018
The continuing use of crude oil and development of the oil industry have resulted in complex hydrocarbon mixtures becoming common environmental contaminants. These contaminants, such as oil sands process affected water (OSPW) and crude oil, are especially of concern in aquatic ecosystems. OSPW...
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Fall 2018
Protein kinases are critical players in cell signaling processes and their activity leads to the phosphorylation of substrates, often regulating enzymatic activity. 518 protein kinases are encoded in the human genome, however, there are many features within the catalytic domain of these proteins...
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The evaluation of toxic effects induced by exposure of mammals to oil sands process-affected water and its organic fraction
DownloadSpring 2018
Oil sands process-affected water (OSPW) produced by the surface-mining oil sands industry in Alberta, has been shown to be toxic to a variety of organisms. Much of this toxicity has been attributed to the dissolved organic compounds, primarily naphthenic acids (NAs). Under a no-release practice,...
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The impacts of metal and salts similar in composition to Oil sands processes affected water (OSPW) on Rainbow trout respirometry, gill structure, and gill enzyme dynamics
DownloadFall 2018
Remediation of Northern Athabasca Oil sands areas has become an essential goal for engineers, biologists and industry stakeholders. Tailing ponds containing oil sand process-affected water (OSPW) have been growing in number as a byproduct of bitumen extraction activity. Treatment of OSPW can...
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Fall 2018
Desmosomes are large, complex protein assemblies which, at the most fundamental level, facilitate cellular adhesion. On a grander scale, desmosomes, and more specifically desmosomal networks, are critical for the maintenance of tissue integrity. They link the cytoskeletons of adjacent cells...
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Fall 2018
Chloride intracellular channel (CLIC) proteins comprise six members CLIC1–CLIC6 in mammals and mediate functions not fully known. Their founding member was isolated from bovine kidney using the chloride channel inhibitor indanyloxyacetic acid-94, so CLICs were assumed to be typical anion...