Search
Skip to Search Results-
Diabetes in Pregnancy among First Nations Women in Alberta: A Multiphase Mixed Methods Approach
DownloadFall 2013
Background Diabetes in pregnancy is thought to be an important driver of the current epidemic of type 2 diabetes in First Nations populations. Purpose The purpose of this doctoral research was 1) to generate an epidemiological profile of First Nations diabetes in pregnancy in Alberta; and 2) to...
-
The Epidemiology of Venous Thromboembolism in Alberta, Canada: A Population Based Cohort Study.
DownloadSpring 2016
Background: Venous thromboembolism (VTE), comprises both deep vein thrombosis (DVT) and pulmonary embolism (PE). It is a common acute cardiovascular event associated with increased long-term morbidity, disability, all-cause mortality, and high rates of recurrence. Major advances in diagnosis,...
-
Spring 2018
Renal cell carcinoma comprises approximately 2-3% of all malignancies, with the majority, approximately 70%, being clear cell renal cell carcinoma (ccRCC). ccRCC features many cancer hallmarks such as suppressed mitochondrial glucose oxidation, apoptosis-resistance, angiogenesis, immune evasion,...
-
Unveiling the pathway for the nuclear translocation of the large mitochondrial enzyme Pyruvate Dehydrogenase Complex (PDC)
DownloadSpring 2021
Pyruvate dehydrogenase complex (PDC) is a mitochondrial enzyme that links glycolysis to oxidative phosphorylation by decarboxylating glucose-derived pyruvate to produce acetyl-CoA that is used in the Krebs cycle. PDC was initially thought to reside only in the mitochondrial matrix but we recently...