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Skip to Search Results- 5Gänzle, Michael G.
- 5Willing, Benjamin P.
- 4Finlay, B. Brett
- 2Antunes, L. Caetano M.
- 2Croxen, Matthew A.
- 2Dieleman, Levinus A.
- 15Graduate and Postdoctoral Studies (GPS), Faculty of
- 15Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 14Agricultural, Food and Nutritional Science, Department of
- 14Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Agricultural, Life, and Environmental Sciences, Faculty of
- 2Agricultural, Life, and Environmental Sciences, Faculty of/Journal Articles (Agricultural, Life, & Environmental Sciences)
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Spring 2015
Ileocolic resection is frequently performed for Crohn's disease; however, disease commonly recurs early in the neo-terminal ileum. The aim of this thesis was to investigate the microbial and immunologic factors inherent to ileocecal resection as they pertain to post-operative recurrence of...
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The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats
Download2014
Baracos, Vickie, Dieleman, Levinus, Farhangfar, Arazm, Lin, Xiaoxi B., Gänzle, Michael G., Sawyer, Michael B., Valcheva, Rosica, Schieber, Andreas
CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to...
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Understanding the role of Clostridioides difficile and Vitamin D supplementation in shaping the gut microbiome of Canadian infants
DownloadSpring 2019
Introduction: The gut microbiome is shaped during infancy and has an important role in the development of both the immune and metabolic systems. Many early life exposures and events contribute to the composition of this complex intestinal environment, notably early infant diet and breastfeeding....