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Skip to Search Results- 1Adzovie,Elom N
- 1Aghamohammadi Sereshki, Arash
- 1Bhardwaj, Paramjit P
- 1Fahreen, Rajani I.
- 1Ferdousi, Mehnaz I
- 1Fung, Terry L
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Structure-Affinity Relationship Study of Novel Imidazoline Ligands at Imidazoline Binding Sites and α-Adrenoceptors
DownloadFall 2014
Many drugs containing an imidazoline moiety are thought to bind to both imidazoline binding sites (IBS) and α-adrenoceptors (α-AR) to mediate their therapeutic effects. To aid in better characterisation of these binding sites, the structure-affinity relationships of several new series of...
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Spring 2024
Mental disorders are one of the leading health problems affecting Canadian children and youth. Teachers are considered frontline workers in child mental health due to the amount of time children spend at school. Given the high prevalence of mental disorders, and the amount of time teachers spend...
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The Development, Feasibility, Acceptability, and Efficacy of a 12-Week Online Mind-Body Intervention for People with Primary Biliary Cholangitis
DownloadFall 2022
Introduction: Persons with primary biliary cholangitis (PBC) experience significantly higher rates of mental distress, impaired health related quality of life (HrQoL), and fatigue than the general population. While mind-body interventions have been shown to improve mental health and HrQoL, and...
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THE PSYCHOSOCIAL FUNCTIONING OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN EARLY ADULTHOOD IS IMPAIRED
DownloadFall 2012
Inflammatory bowel disease is a chronic disease that is often diagnosed in childhood and adolescence. The objective of this study was to assess the impact of a diagnosis of IBD on the psychosocial functioning in early adulthood. This was a questionnaire-based cross-sectional study comparing...
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Fall 2011
Worldwide, depression is the leading cause of disability However, its etiology is not yet fully understood. The current research investigated the relationship between early cognitive development and adolescent depression. Two studies were conducted using data from a prospective longitudinal...
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Fall 2016
Depression a disabling chronic illness that crosses borders, cultures, and elements of society. It is well known that there are a number of risk factors for depression including younger age, racial minority status, female sex, presence of substance abuse disorders, chronic illness, and lower...
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Spring 2014
This mixed method thesis examined the relationship between social support and early engagement in residential addiction treatment. Study 1 involved a secondary data analysis of a prospective cohort of clients entering a residential addiction treatment program. The multivariate analyses tested...
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The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel Disease
DownloadFall 2014
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...
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Spring 2012
Background The adjacent vertebrae and endplates are important to maintaining the integrity and functions of the intervertebral disc. Yet, they have received relatively little attention and their roles in disc degeneration (DD) and back pain remain unclear. Purpose The purpose of this doctoral...
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Fall 2015
Throughout the twentieth century, tuberculosis (TB) was and continues to be a pressing health problem facing Canadians. Aboriginal peoples living in Canada carry a large burden of the disease with those living in the Prairie Provinces facing TB rates consistently higher than the national average....