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Skip to Search Results- 9Arachidonic acid
- 6Docosahexaenoic acid
- 3Cardiac hypertrophy
- 2Breast milk
- 2Calcium in the body
- 2Cytochrome P450
- 1Aghazadeh Habashi, Ali
- 1Al Lawati, Hanan M
- 1Alsaad,Abdulaziz M
- 1Anderson, Warren G.
- 1Beaulieu, Michael J.
- 1Douglas, Claire
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Role of CYP-mediated Arachidonic Acid Metabolites in Development of Cardiac Hypertrophy and Chronic Doxorubicin-induced Cardiotoxicity
DownloadSpring 2013
Drug-induced cardiotoxicity is classified as a predisposing factor leading to cardiac hypertrophy and heart failure. Of importance, doxorubicin (DOX, adriamycin) is considered as an effective anticancer agent whose major limiting side effect is cardiotoxicity. Of importance, several studies...
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The role of cytochrome P450 derived arachidonic acid metabolites against Angiotensin II-induced cardiac hypertrophy in Sprague Dawley rats and the RL-14 cell line
DownloadFall 2015
Several cytochrome P450 (CYP) enzymes and their arachidonic acid (AA) metabolites play essential roles in the maintenance of cardiovascular health, and their alteration gives rise to a number of cardiovascular diseases, including cardiac hypertrophy and heart failure. Recent data demonstrated...
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The role of the dietary long chain polyunsaturated fatty acid, docosahexaenoic acid, in prevention of breast cancer and its’ efficacy during neoadjuvant breast cancer chemotherapy
DownloadSpring 2021
Newell, Heather Marlene Marnie
Breast cancer (BC) is the most frequently diagnosed and the second leading cause of cancer related death in Canadian women. Docosahexaenoic acid (DHA) is an n-3 long chain polyunsaturated fatty acid (LCPUFA) that has shown efficacy in reducing BC cell growth, however its’ role in prevention of BC...