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Skip to Search Results- 3Field, Catherine J.
- 2Ametaj, Burim N.
- 2Dervishi, Elda
- 2Hailemariam, Dagnachew
- 2Proctor, Spencer D.
- 2Ruth, Megan R.
- 22Graduate and Postdoctoral Studies (GPS), Faculty of
- 22Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 9Agricultural, Food and Nutritional Science, Department of
- 9Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Biological Sciences, Department of
- 2Biological Sciences, Department of/Journal Articles (Biological Sciences)
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A large deletion virus reveals the presence of previously uncharacterized vaccinia virus inhibitors of NF-kB signaling
DownloadFall 2010
The classical Nuclear Factor kappa B (NF-κB) signaling pathway is an important regulator of inflammation and innate immune responses. Poxviruses, including vaccinia virus, encode multiple immune evasion proteins, including a growing number of NF-κB inhibitors. To determine if additional vaccinia...
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A microsatellite polymorphism in the gamma interferon gene is associated with resistance to gastrointestinal nematodes in a naturally-parasitized population of Soay sheep
Download2001
Pemberton, J. M., Coltman, D. W., Pilkington, J. G., Wilson, K., Stear, M. J.
Abstract: Free-living Soay sheep (Ovis aries) on the island of Hirta, St Kilda, Scotland, are naturally parasitized bq gastrointestinal nematodes, predominantly Teladorsagia circumcincta. In this paper we show that reduced faecal egg counts (FEC) are associated with an allele at a microsatellite...
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Alterations of innate immunity reactants in transition dairy cows before clinical signs of lameness
Download2015
Dervishi, Elda, Hailemariam, Dagnachew, Zhang, Guanshi, Goldansaz, Seyed A., Deng, Qilan, Dunn, Suzanna M., Ametaj, Burim N.
The objectives of this study were to evaluate metabolic and innate immunity alterations in the blood of transition dairy cows before, during, and after diagnosis of lameness during periparturient period. Blood samples were collected from the coccygeal vain once per week before morning feeding...
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Fall 2010
Mast cells are immune cells important in innate immunity. Besides their role in asthma and allergies, mast cells are critical effector cells against various pathogens. Mast cells are established to be protective against bacterial infections, but little is known about their functions in viral...
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Fall 2017
Most antivirals target viral proteins and are specific for only one virus, or even one viral genotype. Whereas viral proteins are encoded in the plastic viral genome, virion lipids are not and their rearrangements during fusion of the virion envelope to cellular membranes are conserved among...
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Birth Weight, Intrauterine Growth Retardation and Fetal Susceptibility to Porcine Reproductive and Respiratory Syndrome Virus
Download2014
Ashley, C., Foxcroft, G., Plastow, G., Harding, J. C. S., Lunney, J. K., Ladinig, A.
The severity of porcine reproductive and respiratory syndrome was compared in pregnant gilts originating from high and low birth weight litters. One-hundred and eleven pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus on gestation day 85 (±1) were...
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Campylobacter jejuni colonization is associated with a dysbiosis in the cecal microbiota of mice in the absence of prominent inflammation
Download2013
Selinger, L. Brent, Inglis, G. Douglas, Uwiera, Richard R. E., Lone, Abdul, Xu, Yong
Background Campylobacter jejuni causes enterocolitis in humans, but does not incite disease in asymptomatic carrier animals. To survive in the intestine, C. jejuni must successfully compete with the microbiota and overcome the host immune defense. Campylobacter jejuni colonization success varies...
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Spring 2014
The introduction of WNV into North America in 1999 was followed by rapid spread throughout the continent. Today, WNV is an endemic pathogen in the west, with thousands of cases of severe infection reported annually. In addition to traditional vaccine research, there is an urgent need to...
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Characterization of the cold stress-induced cyanobacterial DEAD-box protein CrhC as an RNA helicase
Download2000
Owttrim, George W., Yu, Esther
We have shown previously that CrhC is a unique member of the DEAD-box family of RNA helicases whose expression occurs specifically under conditions of cold stress. Here we show that recombinant His-tagged CrhC, purified from Escherichia coli, is an ATP-independent RNA binding protein possessing...
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Fall 2024
Viral diseases are a constant threat that have profound impact on global health, economics and societies. Understanding virus-host interactions is key for advancing our knowledge of viral replication and pathogenesis, and thus for the development of effective antiviral strategies to better...