Search
Skip to Search Results- 28Meta-analysis
- 27Alzheimer's disease
- 6Systematic reviews
- 4Dementia
- 3Amyloid precursor protein
- 3Cognitive impairment
- 30Graduate and Postdoctoral Studies (GPS), Faculty of
- 30Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 9Nursing, Faculty of
- 7Nursing, Faculty of/Chronicity
- 5Medicine and Dentistry, Faculty of
- 4Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
-
A meta-analysis on the reading comprehension skills of individuals with autism spectrum disorders
Download2013
Brown, Heather, Oram-Cardy, Janis, Johnson, Andrew
This meta-analysis examined 36 studies comparing autism spectrum disorder (ASD) and control groups in reading comprehension. Three moderators (semantic knowledge, decoding skill, PIQ) and two text types (high vs. low social knowledge) were examined as predictors of reading comprehension in ASD....
-
Spring 2016
There is ample evidence that autophagy is affected in Alzheimer’s disease (AD) but the causes, the nature of the dysfunction and the mechanisms of autophagy impairment are unclear. Autophagy depends on vesicular trafficking and membrane fusion, events that rely on several protein complexes and...
-
Fall 2019
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid beta (Aβ) peptide. It has been proposed that AD pathology is transmissible by a “prion-like” mechanism through extracellular vesicles (EVs) that contain Aβ. In this context, EVs describe both microvesicles and exosomes,...
-
Spring 2022
Carotid atherosclerosis is responsible for 15-25% of the nearly 8 million first-ever ischemic strokes that occur each year worldwide. This proportion has remained constant over the past three decades, thus suggesting that some patients with carotid atherosclerosis currently receive suboptimal...
-
Fall 2021
The field of animal personality, the study of adaptive among-individual behavioural differences in animal populations, has both exploded in popularity in the last few decades and come under heavy scrutiny by behavioural ecologists. The sudden interest in the field stems from the widespread...
-
Cellular level/distribution of γ-secretase subunit nicastrin and its modulator p23 in the brain
DownloadSpring 2010
The processing of amyloid precursor protein (APP) by β- and γ-secretases produces amyloid β (Aβ) peptide, the principal component of the neuritic plaques found in Alzheimer’s disease (AD) pathology. The enzyme γ-secretase is a multimeric protein consisting of presenilins-1/2 (PS1/PS2), nicastrin,...
-
Spring 2013
Alzheimer’s disease (AD) is a complex neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ)-related peptides derived from the proteolytic processing of amyloid precursor protein (APP). Research over the last two decades has shown that alterations in the levels...