Search
Skip to Search Results- 34Graduate and Postdoctoral Studies (GPS), Faculty of
- 34Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 14Nursing, Faculty of
- 9Nursing, Faculty of/Chronicity
- 3Nursing, Faculty of/Health Systems
- 2Rehabilitation Medicine, Faculty of
-
Roles of the Insulin-like Growth Factor-II/Cation-independent Mannose 6-phosphate Receptor and Cathepsin D in Alzheimer’s Disease Pathology
DownloadSpring 2016
Alzheimer’s disease (AD) is the most common type of senile dementia affecting the elderly. A critical contributing factor to the neurodegeneration and development of AD pathology stems from the processing of amyloid precursor protein (APP), leading to the generation of β-amyloid (Aβ) peptides....
-
Short- and Long-Term Impacts of A Working Memory Intervention for Children with Prenatal Alcohol Exposure
DownloadSpring 2018
This dissertation consists of two studies designed to: (1) determine the neurobehavioural profile reflecting the strengths and limitations of children with Parental Alcohol Exposure (PAE) and (2) evaluate the short- and long-term impacts of a 25-session Cogmed© intervention on improving working...
-
Fall 2020
Tauopathies are a class of neurological disorders associated with the aggregation of the tau protein into neurofibrillary tangles. The most prominent tauopathy is Alzheimer’s disease (AD), which presents as two forms: early onset (familial, fAD) and late onset (sporadic, sAD). sAD does not have a...
-
The effectiveness of Return to Duty Intervention: Evaluating an interdisciplinary approach to supporting Canadian Armed Forces members who have physical and non-physical disorders
DownloadSpring 2016
The rate of musculoskeletal and mental health disorders is high in the Canadian Armed Forces, and can preclude service members from being employable and deployable. The aim of this thesis was to analyze the effectiveness of the Return to Duty intervention at decreasing morbidity and assisting...
-
The Impact of an Intervention on Social Skills of Young Children with Prenatal Alcohol Exposure
DownloadSpring 2015
FASD is an umbrella term used to describe the continuum of effects that result from prenatal alcohol exposure (PAE) on the developing brain, which causes a multitude of behavioural impairments, including deficits in adaptive behaviours such as social skills. Although there are many interventions...
-
Thermal response of amyloidogenic elements in cultured N2a cells: potential relevance to Alzheimer’s disease pathology
DownloadFall 2020
Alzheimer’s disease (AD) weighs a large burden on health care systems, families and caregiving networks around the world. It is the most common dementia afflicting elderly individuals, and causes many debilitating symptoms, including memory loss, mood swings and confusion which progress in...
-
2011
Estabrooks, C.A., O'Rourke, H.M., Cobban, S., Squires, J.E., Bostrom, A.M., Hutchinson, A.M.
Background: In the past forty years, many gains have been made in our understanding of the concept of research utilization. While numerous studies exist on professional nurses' use of research in practice, no attempt has been made to systematically evaluate and synthesize this body of literature...
-
Umbrella Review of Psychosocial Interventions Mediated through Assistive Technology for Children with Autism Spectrum Disorder
DownloadFall 2017
Aim: In the past 20 years, a large body of autism spectrum disorder (ASD) intervention research has emerged. In addition, the number of systematic reviews (SRs) aimed at synthesizing that body of research has grown substantially. The present umbrella review collates information from multiple...
-
Use of autobiographical memory cues as cognitive support for episodic memory: Comparison of individuals with mild-stage Alzheimer's disease and healthy older adults
DownloadFall 2009
The purpose of the study was to examine the effectiveness of autobiographical memories to support the improvement of episodic memory (i.e., word recall) in patients with mild- stage Alzheimer’s Disease (AD) and healthy older adults. Participants included 20 healthy young-old adults (M Age =...