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Subject: Alpha and beta Peptides
Departments: Department of Chemistry
Item type: Thesis
Languages: English
Collections: Graduate and Postdoctoral Studies (GPS), Faculty of
Collections: Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
Supervisors: Hall, Dennis (Department of Chemistry)
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Improved Gram-Scale Procedure for MIBA-Catalyzed Direct Amidation and Its Application to the Preparation of alpha and beta Peptides
DownloadFall 2015
Direct condensation between a carboxylic acid and amine must overcome the initial formation of a thermodynamically stable and unreactive carboxylate-ammonium salt, providing the amide product only at very high temperatures (over 160 oC) that are incompatible with many functionalized molecules....
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