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Fall 2021
Chronological aging is one of the greatest risk factors of tauopathies, yet our understanding about the underlying molecular mechanism is limited. Studying physiological aging often requires an extended timeline and thus presents a significant hurdle for modeling late-onset disorders. In this...
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Insulin signaling, mitochondrial DNA copy number regulation and aging in Caenorhabditis elegans
DownloadFall 2010
Mitochondrial dysfunction is considered as a key mechanism of aging but little is known about the impact of mitochondrial biogenesis. Mitochondrial DNA (mtDNA) copy number control is an important aspect of mitochondrial biogenesis and is highly regulated in eukaryotic organisms. By studying mtDNA...
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