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Skip to Search Results- 20Graduate and Postdoctoral Studies (GPS), Faculty of
- 20Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 15Chemistry, Department of
- 15Chemistry, Department of/Journal Articles (Chemistry)
- 4Biological Sciences, Department of
- 4Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Identifying nonspecific ligand binding in electrospray ionization mass spectrometry using the reporter molecule method
2009
Kitova, Elena N., Klassen, John S., Sun, Nian, Sun, Jiangxiao
The application of the reporter molecule (Mrep) method for identifying nonspecific complexes in the ES-MS analysis of protein-ligand and DNA-ligand interactions in vitro is described. To test the reliability of the method, it was applied to the ES-MS analysis of protein-carbohydrate complexes...
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Fall 2019
Lateral–torsional buckling is a stability-related failure mode of unbraced or insufficiently braced flexural members. In recent years, several concerns have been raised regarding the adequacy of the Canadian steel design standard, CSA S16-14, in characterising the lateral–torsional buckling...
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Modeling, Analysis and Advanced Control of Voltage- and Current-Source Converters in Renewable Energy-Based Active Distribution Systems
DownloadSpring 2016
This thesis addresses the integration of renewable energy resources into the grid-connected and isolated distribution systems using voltage- and current-source converters. Motivated by its promising potential and attractive features, a one-stage current-source converter (CSC) is selected as an...
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Nonspecific interactions between proteins and charged biomolecules in electrospray ionization mass spectrometry
Download2010
Soya, Naoto, Klassen, John S., Kitova, Elena N., Sun, Nian
An investigation of the nonspecific association of small charged biomolecules and proteins in electrospray ionization mass spectrometry (ES-MS) is described. Aqueous solutions containing pairs of proteins and a small acidic or basic biomolecule that does not interact specifically with either of...
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Nonspecific interactions between proteins and charged biomolecules in electrospray ionization mass spectrometry
Download2010
Kitova, Elena N., Sun, Nian, Klassen, John S., Soya, Naoto
An investigation of the nonspecific association of small charged biomolecules and proteins in electrospray ionization mass spectrometry (ES-MS) is described. Aqueous solutions containing pairs of proteins and a small acidic or basic biomolecule that does not interact specifically with either of...
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Novel feed enzyme delivery method: Binding exogenous feed enzymes to Bacillus spores to improve enzyme stability and total tract digestibility
DownloadFall 2018
The effects of binding feed enzymes to Bacillus subtilis (strain RK28) spores on enzyme stability and digestion in cattle were studied in comparison to unbound enzymes. Optimal conditions for adsorbing six different enzymes (α-amylase, β-glucanase, feruloyl esterase, phytase, purified xylanase,...
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2009
Hillen, T., Lewis, M.A., Lee, J.M.
In this paper, we consider spatial predator–prey models with diffusion and prey-taxis. We investigate necessary conditions for pattern formation using a variety of non-linear functional responses, linear and non-linear predator death terms, linear and non-linear prey-taxis sensitivities, and...
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2007
Berry, K.M., Erickson, T., Callander, D., Koss, R., Ngai, J., Stout, J., Waskiewicz, A.J., Wuennenberg-Stapleton, K., Moens, C.B., Hagey, D.W., French, C.R.
Background Pbx genes encode TALE class homeodomain transcription factors that pattern the developing neural tube, pancreas, and blood. Within the hindbrain, Pbx cooperates with Hox proteins to regulate rhombomere segment identity. Pbx cooperates with Eng to regulate midbrain-hindbrain boundary...
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Protein-glycolipid interactions studied in vitro using ESI-MS and nanodiscs: Insights into the mechanisms and energetics of binding
Download2015
Han, Ling Han, Kitova, Elena N., Klassen, John S., Pluvinage, Benjamin, Lin, Hong, Nikjah, Sanaz, Li, Jun, Boraston, Alisdair B.
Electrospray ionization-mass spectrometry (ESI-MS) analysis combined with the use of nanodiscs (NDs) to solubilize glycolipids (GLs) has recently emerged as a promising analytical method for detecting protein–GL interactions in vitro and, when applied to libraries of GLs, ranking their...
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Protein-glycolipid interactions studied in vitro using ESI-MS and nanodiscs: Insights into the mechanisms and energetics of binding
Download2015
Nikjah, Sanaz, Boraston, Alisdair B., Lin, Hong, Kitova, Elena N., Li, Jun, Pluvinage, Benjamin, Han, Ling Han, Klassen, John S.
Electrospray ionization-mass spectrometry (ESI-MS) analysis combined with the use of nanodiscs (NDs) to solubilize glycolipids (GLs) has recently emerged as a promising analytical method for detecting protein–GL interactions in vitro and, when applied to libraries of GLs, ranking their...