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Skip to Search Results- 2Al Sayah, Fatima
- 1Adame Perez, Stephany
- 1Al-Adra, David P.
- 1Albalawi, Zaina H
- 1Anderson, Sarah J
- 1Asaad, Ghada A
- 7Department of Agricultural, Food, and Nutritional Science
- 6Department of Mechanical Engineering
- 6Department of Surgery
- 4School of Public Health
- 3Department of Educational Psychology
- 3Faculty of Pharmacy and Pharmaceutical Sciences
- 3Olfert, Jason (Mechanical Engineering)
- 2Johnson, Jeff A. (School of Public Health Sciences, University of Alberta)
- 2Williams, Beverly (Faculty of Nursing, University of Alberta)
- 1Al Hamarneh, Yazid (Pharmacology)
- 1Altabtbaei, Khaled (Periodontics)
- 1Anderson, Colin (Medical Microbiology and Immunology and Surgery)
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Characterization of Particulate Matter Morphology and Volatility for Two Direct-Injection Engines
DownloadFall 2015
Particulate matter emitted from two direct injection engines has been characterized by morphology, volatility, mass-mobility exponent, effective density, and size distribution using tandem measurements from a centrifugal particle mass analyzer (CPMA) and differential mobility analyzers (DMA). The...
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Clinical and Translational Studies Advancing Clinical Implementation of Stem Cell-Derived Islet Transplantation
DownloadSpring 2024
Twenty-years ago Shapiro et al. revolutionized islet transplantation (ITx), realizing the potential for a cell-based diabetes treatment. Despite improvements, ITx remains restricted by organ donor limitations and immunosuppression. Stem cell (SC)-derived ITx (SC Tx) could eliminate these...
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Contributions of Bim and Nur77 to multiple mechanisms of T cell tolerance following high affinity antigen encounter
DownloadSpring 2015
Prevention of autoimmune disease requires the elimination or inactivation of T cells that are highly reactive to self-peptides. During T cell development in the thymus, self-reactive thymocytes undergo negative selection upon receiving a high affinity T cell receptor (TCR) signal following...
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Fall 2012
Establishing mixed hematopoietic chimerism is a promising approach to develop donor-specific tolerance to transplanted organs. Establishing tolerance may eliminate the need for long-term immunosuppressive therapy, prevent chronic rejection and in the case of Type 1 Diabetes (T1DM), reverse...
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Development of Empirical Models to Predict Deposition of Aerosols in the Extrathoracic Airways of Children
DownloadSpring 2012
The experimental studies described in this thesis were performed with the goal of measuring deposition of aerosols, inhaled either nasally or orally, in the extrathoracic airways of children in different age groups. We pursued in vitro methods and characterized the deposition of aerosols in the...
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Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes
DownloadFall 2012
While guidelines for seasonal influenza vaccinations single out working age (< 65) adults with diabetes, vaccination rates in this group remain below national targets. Historically, there has been limited evidence to support these guidelines. This dissertation comprises four studies investigating...
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Drug Exposure Definition and Healthy User Bias Impacts on the Evaluation of Oral Anti Hyperglycemic Therapies
DownloadFall 2017
Accurate estimation of medication use is an essential component of any pharmacoepidemiological research as exposure misclassification will threaten study validity and lead to spurious associations. Many pharmacoepidemiological studies use simple definitions, such as the categorical “any versus no...
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Fall 2011
Islet transplantation is promising treatment for certain patients with type 1 diabetes who experience recurrent episodes of hypoglycemia with unawareness. One opportunity to improve on islet transplant outcomes and potentially broaden the recipient population, is to reduce the early post...
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Evaluation of Mask and Mask Material Suitability for COVID-19 Transmission Protection and Influence of Face Velocity and Exhaled Breath Condensate on Filtration Efficiency
DownloadSpring 2022
Facemask use has been a key public health measure in response to the SARS CoV-2 pandemic; they are used to reduce airborne transmission of the disease amongst the public. The facemasks used by the public are non-medical in nature and therefore are not regulated like medical masks. Cloth masks,...
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Exploring the Relationship Between Depression and Adherence in Individuals with Type 2 Diabetes
DownloadFall 2020
Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...