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Influence of lipids (arachidonic acid and cholesterol) on calcium signalling in rodent pancreatic beta cells
DownloadFall 2010
Ca2+ is an important mediator of stimulus-secretion coupling in beta cells of the pancreatic islets, which secrete insulin in response to elevation in plasma glucose concentration. I studied the actions of two lipids, arachidonic acid (AA) and cholesterol, on enzymatically-dissociated single...
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Investigating the Influence of Therapeutic Hypothermia on Stroke-Induced Intracranial Pressure in a Rat Model of Intracerebral Hemorrhage
DownloadSpring 2016
Elevated intracranial pressure (ICP) is a potentially life threatening complication after intracerebral hemorrhagic stroke (ICH). Animal and clinical studies suggest that mild (~33ºC) therapeutic hypothermia (TH) reduces ICP after ischemic stroke and traumatic brain injury (TBI). Since TH has...
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