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Influence of lipids (arachidonic acid and cholesterol) on calcium signalling in rodent pancreatic beta cells
DownloadFall 2010
Ca2+ is an important mediator of stimulus-secretion coupling in beta cells of the pancreatic islets, which secrete insulin in response to elevation in plasma glucose concentration. I studied the actions of two lipids, arachidonic acid (AA) and cholesterol, on enzymatically-dissociated single...
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Investigating the Influence of Therapeutic Hypothermia on Stroke-Induced Intracranial Pressure in a Rat Model of Intracerebral Hemorrhage
DownloadSpring 2016
Elevated intracranial pressure (ICP) is a potentially life threatening complication after intracerebral hemorrhagic stroke (ICH). Animal and clinical studies suggest that mild (~33ºC) therapeutic hypothermia (TH) reduces ICP after ischemic stroke and traumatic brain injury (TBI). Since TH has...
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Fall 2013
A basic tenet of comparative studies of the brain is that the larger size of any neural structure is related to the need for progressing more complex or larger quantities of information, the so call Jerison's “principle of proper mass”. Base on this principle, variation of the absolute and...