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- 1Angiotensin II
- 1Cardiac fibrosis
- 1Cardiac hypertrophy
- 1Hypertension
- 1Hypertensive cardiac remodelling
- 1Matrix metalloproteinase
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Spring 2011
Angiotensin II signals cardiovascular disease through metalloproteinases including MMP-2, MMP-7 and ADAM-17/TACE. We hypothesized that these metalloproteinases regulate each other at the transcriptional level. Further, MMP-2, being a major gelatinase in cardiac and vascular tissue, could mediate...
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