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- 1Cell Adhesion
- 1Congenital Hereditary Endothelial Dystrophy
- 1Corneal endothelial cell
- 1Endothelial Corneal Dystrophy
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2018-01-01
Imagine a life with unexpected deterioration of vision leading to complete blindness. Surprisingly, 1 in 20 people in North America lose their ability to see clearly around 40 years of age due to a genetic blinding disease called Fuchs’ dystrophy. The disease affects the outermost layer of the...
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SLC4A11 in Blinding Endothelial Corneal Dystrophies: Characterization, Molecular Defect and Potential Therapeutic Strategy
DownloadFall 2019
Endothelial Corneal Dystrophies (ECD), genetic blinding diseases with a heterogeneous pathophysiology, are the leading cause of endothelial keratopathy (corneal transplants). Patients manifest symptoms, including corneal edema with increased corneal thickness and loss of corneal endothelial cells...