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The human neuraminidase enzyme, NEU3, regulates integrin-mediated cell migration via changes in glycolipid composition
DownloadFall 2013
The human neuraminidase enzyme, NEU3, is known to cleave sialic acid from ganglioside substrates. However, the biological effects of this cleavage are not clearly understood. This thesis describes our studies of the regulation of β1-integrins by neuraminidase enzymes, and the role of gangliosides...
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