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Biogenesis of Porin of the Outer Mitochondrial Membrane Involves an Import Pathway via Receptors and the General Import Pore of the TOM Complex
Download2001
Nargang, F. E., Pfanner, N., Neupert, W., Blachly-Dyson, E., Forte, M., Krimmer, T., Ryan, M. T., Kassenbrock, K., Rapaport, D., Douglas, M. G., Meisinger, C.
Abstract: Porin, also termed the voltage-dependent anion channel, is the most abundant protein of the mitochondrial outer membrane. The process of import and assembly of the protein is known to be dependent on the surface receptor Tom20, but the requirement for other mitochondrial proteins...
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Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes
Download2004
Habib, S.J., Panneels, V., Vasiljev, A., Prokisch, H., Nussberger, S., Neupert, W., Sinning, I., Nargang, F.E., Ahting, U., Rapaport, D., Go, N.E., Kozany, C.
Precursor proteins of the solute carrier family and of channel forming Tim components are imported into mitochondria in two main steps. First, they are translocated through the TOM complex in the outer membrane, a process assisted by the Tim9/Tim10 complex. They are passed on to the TIM22...