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Skip to Search Results- 3Gänzle, Michael G.
- 2Sawyer, Michael B.
- 1Baracos, Vickie
- 1Baracos, Vickie E.
- 1Bibova, Ilona
- 1Cristescu, Bogdan
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Diet and environment shape fecal bacterial microbiota composition and enteric pathogen load of grizzly bears
Download2011-01-01
Northrup, Joseph M., Cristescu, Bogdan, Schwab, Clarissa, Stenhouse, Gordon B., Gänzle, Michael G.
Background Diet and environment impact the composition of mammalian intestinal microbiota; dietary or health disturbances trigger alterations in intestinal microbiota composition and render the host susceptible to enteric pathogens. To date no long term monitoring data exist on the fecal...
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2012
Ketabi, Ali, Baracos, Vickie E., Field, Catherine J., Lin, Xiaoxi, Xue, Hongyu, Bibova, Ilona, Gänzle, Michael G., Dieleman, Levinus A., Sawyer, Michael B.
Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota and their functions are thus potential targets for treatment to mitigate CPT-11 toxicity. However, microbiota...
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The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats
Download2014
Baracos, Vickie, Dieleman, Levinus, Farhangfar, Arazm, Lin, Xiaoxi B., Gänzle, Michael G., Sawyer, Michael B., Valcheva, Rosica, Schieber, Andreas
CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to...