Search

2012

Thomson, D., Chisholm, A., Hartling, L., Dryden, D. M.

Background: Overviews of systematic reviews compile data from multiple systematic reviews (SRs) and are a new method of evidence synthesis. Objectives: To describe the methodological approaches in overviews of interventions. Design: Descriptive study. Methods: We searched 4 databases from 2000 to...

2013

Scott, S. D., Johnson, D. W., Klassen, T. P., Bishop, T., Hartling, L.

Introduction Stories may be an effective tool to communicate with patients because of their ability to engage the reader. Our objective was to evaluate the effectiveness of story booklets compared to standard information sheets for parents of children attending the emergency department (ED) with...

2008

Offringa, M., Hartling, L., Craig, J. C., Klassen, T. P.

Children are often touted as being very important members of society because they represent our future. Optimizing their health outcomes has the potential for a huge impact on public health because children are at an early stage in the life trajectory. But it is often unclear how society...

2010

Tjosvold, L., Thomson, D., Vandermeer, B., Klassen, T. P., Cohen, E., Hartling, L.

Background The objective of this study was to describe randomized controlled trials (RCTs) and controlled clinical trials (CCTs) in child health published between 1948 and 2006, in terms of quantity, methodological quality, and publication and trial characteristics. We used the Trials Register...

2013

Scott, S. D., Moher, D., Klassen, T. P., Hartling, L., Hamm, M. P.

Introduction A research-practice gap exists between what is known about conducting methodologically rigorous randomized controlled trials (RCTs) and what is done. Evidence consistently shows that pediatric RCTs are susceptible to high risk of bias; therefore novel methods of influencing the...

2004

Klassen, T. P., McConnell, D., Craig, W. R., Wiebe, N., Hartling, L., Bellemare, S., Russell, K.

Background Despite treatment recommendations from various organizations, oral rehydration therapy (ORT) continues to be underused, particularly by physicians in high-income countries. We conducted a systematic review of randomised controlled trials (RCTs) to compare ORT and intravenous therapy...

2008

Russell, K., Liang, Y., O'Gorman, K., Klassen, T. P., Friesen, C., Dryden, D. M., Wild, T. C., Durec, T.

Background: Methamphetamine (MA) is a potent stimulant that is readily available. Its effects are similar to cocaine, but the drug has a profile associated with increased acute and chronic toxicities. The objective of this systematic review was to identify and synthesize literature on risk...

2011

Bialy, L., Klassen, T. P., Hartling, L., Vandermeer, B., Johnson, D., Milne, A., Plint, A., Fernandes, R. M.

Objective To evaluate and compare the efficacy and safety of bronchodilators and steroids, alone or combined, for the acute management of bronchiolitis in children aged less than 2 years. Design Systematic review and meta-analysis. Data sources Medline, Embase, Central, Scopus, PubMed, LILACS,...

2010

Hartling, L., Johnson, D., Scott, S. D., Bishop, T., Klassen, T. P., Pandya, R.

BACKGROUND: Stories may be an effective tool to communicate with and influence patients because of their ability to engage the reader. The objective of this paper is to describe the development of a story-based intervention for delivery of health evidence to parents of children with croup for use...

2005

Cramer, K., Hartling, L., Wiebe, N., Klassen, T. P., Crumley, E. T.

Background Systematic reviewers seek to comprehensively search for relevant studies and summarize these to present the most valid estimate of intervention effectiveness. The more resources searched, the higher the yield, and thus time and costs required to conduct a systematic review. While there...