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Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project
Download2015
Tosser-Klopp, G., Zhou, H., Palti, Y., Nanduri, B., Tixier-Boichard, M., Silverstein, J., Plastow, G. S., Sarropoulou, E., Brauning, R., Zhao, S., Rohrer, G. A., Elsik, C. G., Cheng, H. H., Giuffra, E., Notredame, C., Khatib, H., Vilkki, J., Couldrey, C., Archibald, A. L., Tellam, R. L., Schmidt, C. J., Reecy, J. M., Clarke, L., Huang, L. S., Groenen, M. A., McEwan, J. C., Burt, D. W., Kim, H., Bottema, C. D., Kijas, J. W., Dalrymple, B. P., White, S. N., Burgess, S. C., Hayes, B. J., McCarthy, F. M., Moore, S., Foissac, S., Lunney, J. K., Andersson, L., Tuggle, C. K., Casas, E.
We describe the organization of a nascent international effort, the Functional Annotation of Animal Genomes (FAANG) project, whose aim is to produce comprehensive maps of functional elements in the genomes of domesticated animal species.
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2006
Geverink, N. A., Plastow, G. S., Foury, A., Gil, M., Gispert, M., Moisan, M. P., Hortós, M., Gort, G., Font i Furnols, M., Mormède, P.
The gene (Cbg) encoding cortisol-binding globulin (CBG) has been proposed as a candidate gene to explain genetic variation in cortisol secretion and carcass composition in pigs. The objective of this study was to evaluate the association between CBG and pork quality in 5 European breeding lines,...
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Development of carcass cuts, organs, body tissue and chemical body composition during growth of pigs
Download2006
Landgraf, S., Roehe, R., Plastow, G. S., Kalm, E., Looft, H., Susenbeth, A., Knap, P. W.
A serial slaughter trial was carried out to examine the developmental change of physical and chemical body composition in pigs highly selected for lean content. A total of 48 pigs (17 females and 31 castrated males) were serially slaughtered and chemically analysed. Eight pigs were slaughtered at...
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2010
M. E. R. Dugan, Juárez, M., Basarab, J. A., Baron, V. S., Aalhus, J. L., McAllister, T. A., Aldai, N.
Forty feedlot steers were fed a barley-grain-based finishing diet typical for western Canada, with two levels of supplementary vitamin E (468 or 1069 IU head-1 d-1) and the effect on backfat trans-18:1 isomeric profile was determined. Feeding 1068 IU vitamin E reduced the total trans-18:1 content...
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Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene
Download2015
Sällman Almén, M., Liao, X., Stothard, P., Henegar, C., Van Doormaal, B., Rubin, C. -J., Andersson, L., Barsh, G. S., Ito, S., Plastow, G., Wakamatsu, K., Dorshorst, B.
Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant Black (MC1RD) and Recessive Red (MC1Re). A...
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2006
Hassanali, M., Stothard, P., Knox, C., Wishart, D.S., Shrivastava, S., Guo, A., Woolsey, J.
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug (i.e. chemical) data with comprehensive drug target (i.e. protein) information. The database contains .4100 drug entries including .800 FDA approved small molecule and biotech drugs as well as .3200...
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Effects of calf- and yearling-fed beef production systems and growth promotants on production and profitability
Download2013
Baron, V. S., López-Campos, O., Aalhus, J. L., Basarab, J. A., Okine, E. K.
In each of 2 yr, 112 spring-born steers were used to evaluate the effect of calf-fed vs. yearling-fed with and without growth implant and β-adrenergic agonist on production parameters and economic potential. Steers were grouped into: (1) non-implanted feeders harvested at 11–14 mo of age, (2)...
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Effects of production system and growth promotants on the physiological maturity scores in steers
Download2014
Aalhus, J. L., Basarab, J. A., N. Prieto, I. L., López-Campos, Ó., Larsen, M.
Over a 2-yr period, 224 crossbred steers were allotted to a 2×2×2 factorial arrangement of treatments to determine the effect of the production system (calf-fed vs. yearling-fed), growth implant strategy (non-implanted vs. implanted) and β-agonist supplementation (no ractopamine vs. ractopamine)...
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Estimation of genetic and phenotypic parameters for ultrasound and carcass merit traits in crossbred beef cattle
Download2014
Bruce, H. L., Plastow, G. S., Moore, S. S., Wang, Z., Nkrumah, D., Miar, Y., Durunna, O.
Ultrasound measurements of 852 crossbred steers along with carcass merit measurements on 756 of them were used to examine their genetic and phenotypic parameters. Traits including ultrasound backfat thickness (UBF), ultrasound ribeye area (UREA), ultrasound marbling (UMAR), carcass weight (CWT),...
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Expansion of ruminant-specific microRNAs shapes target gene expression divergence between ruminant and non-ruminant species
Download2013
Kommadath, A., Bao, H., Meng, Y., Plastow, G. S., Stothard, P., Sun, X., Arantes, A. S., Guan, L. L.
Background Understanding how species-specific microRNAs (miRNAs) contribute to species-specific phenotypes is a central topic in biology. This study aimed to elucidate the role of ruminant-specific miRNAs in shaping mRNA expression divergence between ruminant and non-ruminant species. ...