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Skip to Search Results- 2Baracos, Vickie E.
- 2Dieleman, Levinus A.
- 2Field, Catherine J.
- 2Gänzle, Michael G.
- 2Sawyer, Michael B.
- 2Xue, Hongyu
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Environmental particulate matter induces murine intestinal inflammatory responses and alters the gut microbiome
Download2013-01-01
Thiesen, Aducio, Rioux, Kevin P., Tso, Robert, Kish, Lisa, Barkema, Herman W., Madsen, Karen L., Vincent, Renaud, Wine, Eytan, Kaplan, Gilaad G., Hotte, Naomi, Gänzle, Michael G.
Background Particulate matter (PM) is a key pollutant in ambient air that has been associated with negative health conditions in urban environments. The aim of this study was to examine the effects of orally administered PM on the gut microbiome and immune function under normal and inflammatory...
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2012
Ketabi, Ali, Baracos, Vickie E., Field, Catherine J., Lin, Xiaoxi, Xue, Hongyu, Bibova, Ilona, Gänzle, Michael G., Dieleman, Levinus A., Sawyer, Michael B.
Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota and their functions are thus potential targets for treatment to mitigate CPT-11 toxicity. However, microbiota...
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Single and combined supplementation of glutamine and n-3 polyunsaturated fatty acids on host tolerance and tumour response to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11)/5-fluorouracil chemotherapy in rats bearing Ward colon tumour
Download2009
Xue, Hongyu, Sawyer, Michael B., Le Roy, Severine, Dieleman, Levinus A., Baracos, Vickie E., Field, Catherine J.
Prior reports suggest that during irinotecan (7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin; CPT-11) chemotherapy in laboratory rats, the anti-tumour efficacy and diarrhoea toxicity could be modulated by n-3 PUFA and glutamine, respectively. We further examined how these two...