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Skip to Search Results- 14Field, Catherine J.
- 3Kaplan, Bonnie J.
- 2Baracos, Vickie E.
- 2Bell, Rhonda C.
- 2Curtis, Jonathan M.
- 2Dieleman, Levinus A.
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Diabetes-prone BioBreeding rats do not have a normal immune response when weaned to a diet containing fermentable fibre
Download2004
Bell, Rhonda C., Field, Catherine J., Stillie, RoseMarie
Diet is known to modulate the development of diabetes in diabetes-prone BioBreeding (BBdp) rats. The objective of the present study was to determine the effect of fermentable fibre (FF) on immune function in BBdp and diabetes-resistant BioBreeding (BBdr) rats after weaning. Weanling BBdp...
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Effect of providing a formula supplemented with long chain polyunsaturated fatty acids on immunity in full term neonates
Download2008
Robinson, Lindsay E., Field, Catherine J., Clandinin, M. Thomas, van Aerde, John E.
To determine the effect of feeding formula containing long-chain PUFA (LCP) on immune function, healthy term infants were randomised at age 2 weeks to either a standard term formula (Formula; n 14) or the same formula supplemented with the LCP 20 : 4n-6 and 22 : 6n-3 (Formula+LCP; n 16)....
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Feeding long chain (n-3) polyunsaturated fatty acids to obese leptin receptor deficient JCR:LA-cp rats modifies immune function and lipid raft fatty acid composition
Download2009
Ruth, Megan R., Field, Catherine J., Proctor, Spencer D.
Dietary EPA and DHA modulate immunity and thereby may improve the aberrant immune function in obese states. To determine the effects of feeding fish oil (FO) containing EPA and DHA on splenocyte phospholipid (PL) and lipid-raft fatty acid composition, phenotypes and cytokine production,...
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2012
Ketabi, Ali, Baracos, Vickie E., Field, Catherine J., Lin, Xiaoxi, Xue, Hongyu, Bibova, Ilona, Gänzle, Michael G., Dieleman, Levinus A., Sawyer, Michael B.
Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota and their functions are thus potential targets for treatment to mitigate CPT-11 toxicity. However, microbiota...
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2014
Bridgman, Sarah L., Letourneau, Nicole, Field, Catherine J., Azad, Meghan B., Johnston, David W., Kozyrskyj, Anita L., Kaplan, Bonnie J.
Background Probiotic products that may modify the intestinal microbiota are becoming increasingly available and known to consumers due to their potential to prevent or treat many pediatric health conditions. As scientific knowledge of the health benefits of probiotics increases, it is important...
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n-3 fatty acids inhibit transcription of human IL-13: Implications for development of T helper type 2 immune responses
Download2013
Cameron, Lisa, Madsen, Norman, MacLean, Emily, Vliagoftis, Harissios, Field, Catherine J.
Fish oil supplementation during pregnancy has been associated with lower levels of cord blood IL-13, suggesting that the administration of n-3 fatty acids may attenuate the development of allergic disease. The present study aimed to investigate the mechanism by which n-3 fatty acid administration...
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Prenatal micronutrient supplementation and postpartum depressive symptoms in a pregnancy cohort
Download2013
Tough, Suzanne, Gomez, Mariel F., Eliasziw, Misha, Gagnon, Lisa, Field, Catherine J., Kaplan, Bonnie J., Leung, Brenda M., McCargar, Linda
Background Postpartum depression is a serious problem for women and their offspring. Micronutrient supplements are recommended for pregnant women because of their documented protective effects for the offspring, but their potential beneficial effects on maternal mental health are unknown. This...
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Single and combined supplementation of glutamine and n-3 polyunsaturated fatty acids on host tolerance and tumour response to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11)/5-fluorouracil chemotherapy in rats bearing Ward colon tumour
Download2009
Xue, Hongyu, Sawyer, Michael B., Le Roy, Severine, Dieleman, Levinus A., Baracos, Vickie E., Field, Catherine J.
Prior reports suggest that during irinotecan (7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin; CPT-11) chemotherapy in laboratory rats, the anti-tumour efficacy and diarrhoea toxicity could be modulated by n-3 PUFA and glutamine, respectively. We further examined how these two...
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Systematic review of safety and tolerability of a complex micronutrient formula used in mental health
Download2011
Simpson, J. Steven A., Crawford, Susan G., Kaplan, Bonnie J., Field, Catherine J., Burgess, Ellen, Goldstein, Estelle T.
Background Theoretically, consumption of complex, multinutrient formulations of vitamins and minerals should be safe, as most preparations contain primarily the nutrients that have been in the human diet for millennia, and at safe levels as defined by the Dietary Reference Intakes. However, the...
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2013
Ruth, Megan R., Field, Catherine J.
The intestine and the gut-associated lymphoid tissue (GALT) are essential components of whole body immune defense, protecting the body from foreign antigens and pathogens, while allowing tolerance to commensal bacteria and dietary antigens. The requirement for protein to support the immune system...