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Paraspinal muscle morphology, composition and asymmetries: determinants and relation to low back pain and pathology.

  • Author / Creator
    Fortin, Maryse
  • Background The lumbar paraspinal muscles are critical to provide spine stability, maintain proper posture and assist trunk movement. Although considerable attention has been focused on the association between variations in paraspinal muscle morphology and low back pain (LBP), their role in the development and progression of LBP remains unclear. Purpose The purpose of this doctoral work was to identify potential determinants of paraspinal muscle asymmetry, characterize the natural progression of age-related changes in paraspinal muscle over a 15-year period and examine their association with LBP problems, and determine whether paraspinal muscle size, composition and asymmetry are risk indicators for the development of LBP. Materials and Methods Subjects were selected from the pre-existing database of the Twin Spine Study. Data were collected through a structured interview, physical examination and magnetic resonance imaging (MRI). Measurement of the multifidus and erector spinae muscle cross-sectional area (CSA), functional CSA (FCSA) (e.g. fat-free mass) and degree of asymmetry in size and composition was obtained from T2-weighted axial images for 202 men at baseline and 99 men at 15-year follow-up. A novel and highly reliable thresholding technique, allowing for the separation of muscle and fat tissue, was developed to perform quantitative measurements of paraspinal muscle composition. Results and Conclusions Of the factors investigated, the few that were significantly associated with paraspinal muscle asymmetry in cross-sectional analyses included handedness, disc height narrowing, the amount of physical activity performed at work and leisure and familial aggregation. Yet, with the exception of handedness and familial aggregation, the associations were generally inconsistent across muscles and spinal levels and explained little of the variance in paraspinal muscle asymmetry. Over the 15-year follow-up period, the multifidus and erector spinae showed similar morphological changes including a decrease in size and an increase in fatty infiltration and asymmetry. However, no significant correlation was found between the long-term paraspinal muscle changes and LBP history. Moreover, multifidus and erector spinae muscle size, composition and degree of asymmetry do not appear to be major risk factors for the short-term (1-year) or long-term (15-year) development or prognosis of LBP, including sciatica.

  • Subjects / Keywords
  • Graduation date
    2013-11
  • Type of Item
    Thesis
  • Degree
    Doctor of Philosophy
  • DOI
    https://doi.org/10.7939/R3WM14499
  • License
    This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.
  • Language
    English
  • Institution
    University of Alberta
  • Degree level
    Doctoral
  • Department
    • Faculty of Rehabilitation Medicine
  • Specialization
    • Rehabilitation Science
  • Supervisor / co-supervisor and their department(s)
    • Michele Crite Battie, Department of Physical Therapy
  • Examining committee members and their departments
    • Eric Parent/Department of Physical Therapy
    • Arthur Prochazka/Department of Physiology
    • Yan Yuan/School of Public Health
    • Paulo Ferreira/Faculty of Health Sciences/University of Sydney
    • Michele Crites Battie/Department of Physical Therapy