Planar moving flap valve structure for microfluidic control

  • Author / Creator
    Lam, Lawrence
  • This work describes the development of a planar moving flexible valve in polydimethylsiloxane (PDMS) with integrated optics components on a microfluidic device. Applying a positive pressure to a side channel, the fluid inside deforms the flexible PDMS which then redirects the flow in a main stream to an alternate output channel. Simulations of the fluid and solid interaction in two channel configurations are performed in COMSOL® using the Arbitrary Lagrangian-Eulerian (ALE) technique. As a result, the 5 um and 10 um flaps were able to be deformed and redirected by a moderate flow velocity. A silicon master was produced for making PDMS chips using standard replication molding technique. Using a commercial miniature peristaltic pump, a 10 um flap is deflected in the microfabricated biochip by the fluid flowing from the side at an average flow rate of 130 uL/min in a 60 um x 65 um channel.

  • Subjects / Keywords
  • Graduation date
  • Type of Item
  • Degree
    Master of Science
  • DOI
  • License
    This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.
  • Language
  • Institution
    University of Alberta
  • Degree level
  • Department
    • Department of Electrical and Computer Engineering
  • Supervisor / co-supervisor and their department(s)
    • McMullin, Jim (Department of Electrical and Computer Engineering)
  • Examining committee members and their departments
    • Moussa, Walied (Department of Mechanical Engineering)
    • DeCorby, Ray (Department of Electrical and Computer Engineering)