Polbase a repository of biochemical, genetic, and structural information about DNA polymerases.

• Author(s) / Creator(s)

  • Reha-Krantz, L.
  • Jack, W. E.
  • Langhorst, B. S.
  • Nichols, N.

• ABSTRACT Polbase (http://polbase.neb.com) is a freely accessible database of DNA polymerases and related references. It has been developed in a collaborative model with experts whose contributions reflect their varied backgrounds in genetics, structural biology and biochemistry. Polbase is designed to compile detailed results of polymerase experimentation, presenting them in a dynamic view to inform further research. After validation, results from references are displayed in context with relevant experimental details and are always traceable to their source publication. Polbase is connected to other resources, including PubMed, UniProt and the RCSB Protein Data Bank, to provide multi-faceted views of polymerase knowledge. In addition to a simple web interface, Polbase data is exposed for custom analysis by external software. With the contributions of many polymerase investigators, Polbase has become a powerful research tool covering most important aspects of polymerases, from sequence and structure to biochemistry.

• Date created

  2011

• Subjects / Keywords

  • Deoxyribonucleic-Acid
  • Revised Nomenclature

• Type of Item

  Article (Published)

• DOI

  https://doi.org/10.7939/R39N9M

• License

  © Langhorst, B.S., Jack, W.E, Reha-Krantz, L., and Nichols, N. (2011). Published by Oxford University Press. All rights reserved. The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org