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A Handheld Bias-Switchable Top-Orthogonal-to-Bottom Electrode (TOBE) 2D Array for Ultrasound and Photoacoustic Applications

  • Author / Creator
    Rahim Sobhani, Mohammad
  • Ultrasound imaging is a noninvasive and widely utilized technique for soft tissue imaging
    in various medical diagnostic and treatment applications. However, conventional
    ultrasound machines face challenges regarding imaging speed and quality due to their
    small probe size, whereas a bigger probe requires many electrical channels for data
    acquisition and processing.
    Deploying a fully-connected 2D array in ultrasound probes is critical for achieving
    high-quality 2D/3D ultrasound images. However, this approach becomes impractical
    when dealing with larger ultrasound arrays. On the other hand, the acquisition and
    processing of data with a higher number of channels result in a reduction in imaging
    speed. Numerous strategies have been developed to address this issue, employing
    multiplexing techniques to limit the number of active elements on arrays. Nevertheless,
    these methods still suffer from lower signal-to-noise ratios (SNR) compared to
    fully connected arrays, leading to smaller aperture sizes and, consequently, restricted
    spatial resolution.
    This doctoral dissertation endeavors to overcome these limitations by pioneering
    the fabrication of unprecedented large bias-sensitive arrays. The focus is on
    top-orthogonal-to-bottom electrode (TOBE) arrays, also called row-column arrays,
    which have demonstrated significant potential as an alternative to fully-wired 2D
    arrays. They offer a substantial reduction in the number of channels required. Previous
    research has shown that innovative imaging techniques involving bias-switchable
    TOBE arrays hold promise compared to earlier non-bias-switchable row-column imaging
    methods and existing Explososcan approaches. However, they often relied on extensive coherent compounding.
    In this work, along with TOBE array fabrication, we introduce ”Ultra-Fast Orthogonal
    Row-Column Electronic Scanning” (uFORCES), an ultrafast coded synthetic
    aperture imaging method. Unlike its FORCES precursor, uFORCES can
    achieve coherent compounding with only a few transmit events, potentially making
    it more robust in the presence of tissue motion. We demonstrate that uFORCES
    has the potential to offer enhanced resolution when compared to Matrix probes with
    beamformers constrained by paraxial approximation. Additionally, unlike current
    Matrix probe technology incorporating microbeamforming, uFORCES enables ultrafast
    imaging at speeds of thousands of frames per second using only row- and
    column-based addressing when coupled with bias-switchable TOBE arrays.
    A hand-held form factor of the TOBE array has been developed and successfully
    tested on cyst phantom targets, and the results are compared with commercial ultrasound
    machines. Also, the feasibility of fabricating a transparent/translucent variant
    of the TOBE array has been briefly investigated, along with reporting some preliminary
    through-illumination photoacoustic imaging from crossed gold wires. This
    bias-switchable TOBE innovation promises to significantly improve ultrasound imaging
    systems’ efficiency and image quality.

  • Subjects / Keywords
  • Graduation date
    Spring 2024
  • Type of Item
    Thesis
  • Degree
    Doctor of Philosophy
  • DOI
    https://doi.org/10.7939/r3-nnf3-5078
  • License
    This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.