Patient-reported outcome measures for adverse events: A systematic review and COSMIN evaluation study

• Author / Creator

  Hancock, Myles T

• ABSTRACT Background: Health care requires constant improvement. Harms in health care are becoming a priority, as is incorporating the patient’s voice in both clinical research and clinical care. Patients have been found to provide a more subjective, detailed perspective of their treatment experiences compared with health care providers; this is especially true of potential harms they have experienced. Measurement instruments must be valid and reliable; a new field of Patient Reported Outcome Measures (PROM) has emerged to capture the patient’s perspective and experience. Methods: A systematic review was conducted to identify all patient-reported outcome measures for adverse events (PROM-AE) currently published in the health literature databases. These measures were compared to establish similarities and differences, and to determine if any core characteristics existed. Results: The most commonly used PROM AE in clinical research and clinical practice were evaluated further with regards to their measurement properties. Conclusion: Important gaps, such as minimal harms reporting in clinical research and practice, were identified that could help advance the field of PROM AE and thereby enhance patient safety in both research and clinical settings.

• Subjects / Keywords

  • Adverse Events
  • Harms
  • Measurement Properties
  • Validation
  • Systematic reviews
  • COSMIN

• Graduation date

  Fall 2017

• Type of Item

  Thesis

• Degree

  Master of Science

• DOI

  https://doi.org/10.7939/R34Q7R41C

• License

  This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.