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An in-house lab manual for analyzing white matter pathways in children who stutter

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  • Diffusion tensor imaging (DTI) proves to have great potential for investigating the white matter network of the brain. The ability to study these pathways may offer important insight into the neurological differences of people with communication disorders. However, due to the high level of technological complexity, which frequently results in a number of data artifacts, quality control of the data is essential for accurate results (Oguz, 2014). Currently, research in the field of DTI lacks rigorous and uniform DTI data quality check standards. This manuscript will act as an in-house manual describing how to prepare quality diffusion MR data for DTI analysis with two commonly used analysis software, FMRIB Software Library (FSL) and Explore DTI. This manual will highlight the preprocessing stages and data quality analysis for both programs in order to facilitate future research for students and scientists in the field of speech-language pathology.

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    Attribution-NonCommercial 3.0 International