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The Relationship between Health Related Quality of Life and Non-Small Cell Lung Cancer Surgery Open Access


Other title
Lung Cancer
Health Related Quality of Life
Video Assisted Thoracoscopic Surgery
Type of item
Degree grantor
University of Alberta
Author or creator
Gazala, Sayf
Supervisor and department
Bedard, Eric (Department of Surgery)
Kutsogiannis, Jim (Department of Critical Care)
Johnson, Jeffrey (School of Public Health)
Examining committee member and department
Bedard, Eric (Department of Surgery)
Johnson, Jeffrey (School of Public Health)
Eurich, Dean (School of Public Health)
Kutsogiannis, Jim (Department of Critical Care)
School Public Health Sciences
Clinical Epidemiology
Date accepted
Graduation date
Master of Science
Degree level
Objectives: To review the studies those have assessed Quality Of Life (QOL) after Video Assisted Thoracoscopic Surgery (VATS) and Thoracotomy for resection of lung cancer, and to determine the impact of post VATS complications on patients’ QOL Methods: For the review, we performed a systematic review, and included studies based on specific inclusion/exclusion criteria according. To determine the impact of surgical complications on patients’ QOL, we designed a prospective cohort study. Results: 5 observational studies were included in this final review; a qualitative as well as a meta-analysis were used to interpret the results. 44 patients were included in the cohort study, there were significant differences based on the complications grade in QOL of patients undergoing VATS lobectomy for lung cancer. Conclusion: In general patients undergoing VATS resection have a better QOL when compared to thoracotomy up to two years after surgery. Post-operative complications can determine patients’ QOL after surgery.
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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File title: Gazala_Sayf_Fall2012
File author: Sayf Gazala
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