ERA

Download the full-sized PDF of Decision Making Under Risk in Patients with HIVDownload the full-sized PDF

Analytics

Share

Permanent link (DOI): https://doi.org/10.7939/R3CJ87X2S

Download

Export to: EndNote  |  Zotero  |  Mendeley

Communities

This file is in the following communities:

Graduate Studies and Research, Faculty of

Collections

This file is in the following collections:

Theses and Dissertations

Decision Making Under Risk in Patients with HIV Open Access

Descriptions

Other title
Subject/Keyword
decision making
HIV
GDT
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Gilliam, Sara E
Supervisor and department
Fujiwara, Esther (Psychiatry)
Examining committee member and department
Purdon, Scot (Psychiatry)
Power, Chris (Medicine, Medical Microbiology & Immunology)
Dixon, Roger (Psychology
Department
Department of Psychiatry
Specialization

Date accepted
2013-09-30T15:43:19Z
Graduation date
2013-11
Degree
Master of Science
Degree level
Master's
Abstract
Individuals with human immunodeficiency virus (HIV) develop neurocognitive impairments, more frequently as the systemic disease progresses to AIDS. Among HIV-infected persons receiving antiretroviral therapy, executive dysfunctions are very commonly impaired. The present study examined HIV-infected patients’ propensity for risky decision making using the Game of Dice Task (GDT), known to covary with executive dysfunctions. Although other tasks and types of decision making have been reported to be impaired in HIV patients, previous study cohorts were complicated by concurrent substance abuse and other comorbidities. Here we used a relatively comorbidity-free population. HIV-infected patients (N=20) were impaired in the GDT, compared to matched healthy controls (N=20). The HIV-infected group also showed an erratic decision strategy across the task. GDT performance was related to measures of executive functioning. Erratic GDT choices were related to current CD4+ T-cell levels. This study provides the first evidence for impaired risky decision making in an HIV-infected population.
Language
English
DOI
doi:10.7939/R3CJ87X2S
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
Citation for previous publication

File Details

Date Uploaded
Date Modified
2014-04-24T23:59:14.991+00:00
Audit Status
Audits have not yet been run on this file.
Characterization
File format: pdf (Portable Document Format)
Mime type: application/pdf
File size: 1288802
Last modified: 2015:10:12 18:39:53-06:00
Filename: Gilliam_Sara_Fall 2013.pdf
Original checksum: 9ecd3353ae5c3ed1c8e0acd51ec6a46d
Well formed: false
Valid: false
Status message: Invalid page tree node offset=936876
Status message: Unexpected error in findFonts java.lang.ClassCastException: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject cannot be cast to edu.harvard.hul.ois.jhove.module.pdf.PdfDictionary offset=2688
Status message: Invalid Annotation list offset=1212725
Status message: Outlines contain recursive references.
File title: University of Alberta
Activity of users you follow
User Activity Date