ERA

Download the full-sized PDF of Midline location of tumour is a risk factor for postoperative vomiting in children requiring posterior fossa tumour resection.Download the full-sized PDF

Analytics

Share

Permanent link (DOI): https://doi.org/10.7939/R3TD9N739

Download

Export to: EndNote  |  Zotero  |  Mendeley

Communities

This file is in the following communities:

Nursing, Faculty of

Collections

This file is in the following collections:

Health Equity

Midline location of tumour is a risk factor for postoperative vomiting in children requiring posterior fossa tumour resection. Open Access

Descriptions

Author or creator
Neufeld, S.
Dundon, B.
Yu, H.
Newburn-Cook, C.
Drummond, J.
Additional contributors
Subject/Keyword
Postoperative Complications -- Risk Factors -- In Infancy and Childhood
Nausea and Vomiting -- Prevention and Control -- In Infancy and Childhood
Brain Neoplasms -- Surgery -- In Infancy and Childhood
Type of item
Journal Article (Published)
Language
English
Place
Time
Description
Children requiring posterior fossa brain tumour surgery form a unique and significant neuro-oncology population. Postoperative vomiting (POV) is a problem for these children. Also, severe vomiting that is refractory to treatment has been seen clinically in these children, but it is not well described in the literature. A subgroup of children requiring surgery for posterior fossa brain tumours (n=153) from a larger six-year retrospective chart audit (n=249) at two Canadian children's hospitals were reviewed for the presence of no, mild, moderate, and severe POV. Inter-rater reliability was established at 94% following a blinded process of comparing POV severity rankings between two data collector/researchers. Discrepancies were resolved through discussion in order to establish a consensus severity score. Findings from multivariable logistic regression analyses indicated that when age and intraoperative use of ondansetron were controlled for, the location of a tumour in a midline location had no overall effect (adjusted OR=1.37, 95% confidence interval: 0.64-2.96, p=0.43), but greater odds of severe vomiting (adjusted OR=7.08, 95% confidence interval: 2.56-19.64, p<0.001). These results support theories of modulation of vomiting by the medullary midline and clinical observations that children with midline posterior fossa tumours are at greater risk for severe refractory vomiting. The development of clinical practice guidelines and further research to study the effectiveness of novel, multimodal antiemetic therapies are required for this patient population.
Date created
2009
DOI
doi:10.7939/R3TD9N739
License information
Rights
© 2009 Canadian Journal of Neuroscience Nursing. This version of this article is open access and can be downloaded and shared. The original author(s) and source must be cited.
Citation for previous publication
Neufeld, S., Dundon, B., Yu, H., Newburn-Cook, C., & Drummond, J. (2009). Midline location of tumour is a risk factor for postoperative vomiting in children requiring posterior fossa tumour resection. Canadian Journal of Neuroscience Nursing, 31(3), 10-14.
Source
Link to related item

File Details

Date Uploaded
Date Modified
2014-05-12T19:27:35.674+00:00
Audit Status
Audits have not yet been run on this file.
Characterization
File format: pdf (Portable Document Format)
Mime type: application/pdf
File size: 188963
Last modified: 2015:10:12 10:47:31-06:00
Filename: CJNN_2009_31_3.pdf
Original checksum: 5407039a78dc5affac2bd64a1ada0d01
Well formed: false
Valid: false
Status message: Unexpected error in findFonts java.lang.ClassCastException: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject cannot be cast to edu.harvard.hul.ois.jhove.module.pdf.PdfDictionary offset=3104
Page count: 5
Activity of users you follow
User Activity Date