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A comparison of neuromuscular electrical stimulation parameters on increasing corticospinal excitability Open Access


Other title
Corticospinal excitability
Stimulation parameters
Motor cortex
Neuromuscular electrical stimulation
Type of item
Degree grantor
University of Alberta
Author or creator
Hindle, Alyssa R
Supervisor and department
Jones, Kelvin (Physical Education and Recreation)
Collins, Dave (Physical Education and Recreation)
Examining committee member and department
Gorassini, Monica (Biomedical Engineering)
Jones, Kelvin (Physical Education and Recreation)
Roy, Francois (Surgery)
Collins, Dave (Physical Education and Recreation)
Centre for Neuroscience
Physical Education and Recreation

Date accepted
Graduation date
Master of Science
Degree level
In this thesis, experiments that investigated the effects of neuromuscular electrical stimulation (NMES) parameters on corticospinal (CS) excitability are described. The NMES-induced afferent volley can increase CS excitability, which can facilitate neurorehabilitation. However, literature outlining the optimal NMES parameters for increasing CS excitability is limited. In the first project, we found that functional electrical stimulation (NMES with high stimulus intensity and frequency) increased CS excitability, while somatosensory stimulation (NMES with low stimulus intensity and frequency) did not. In the second project, longer pulse durations increased the magnitude of H-reflexes from tibialis anterior, but we found no difference in their effects on CS excitability between pulse durations. These results provide insight for which parameters of NMES best increase CS excitability. Improvements in function resulting from NMES are attributed to the NMES-induced increases in CS excitability, thus identifying how to best increase CS excitability may be important for rehabilitative applications.
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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