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Alberta Research Centre for Health Evidence (ARCHE)
The Alberta Research Centre for Health Evidence (ARCHE), located within the Department of Pediatrics at the University of Alberta, was established in 2000 to serve as a resource to individuals and groups interested in using evidence for decision making.
The mandate of ARCHE is to support and foster the development of evidence-informed practice. To achieve this, ARCHE:
- produces high quality evidence syntheses aimed at high priority issues in health;
- advances the methods of conducting randomized controlled trials (RCTs) and evidence syntheses;
- provides training and mentoring to health care professionals, trainees and students;
- conducts knowledge translation activities to help inform clinical and policy decisions.
Items in this Collection
- 3Bronchiolitis
- 2Cochrane Acute Respiratory Infections Group
- 1Albuterol
- 1Ambulatory Care
- 1Epinephrine
- 1Glucocorticoids
- 2Bialy, Liza M.
- 2Fernandes, Ricardo M.
- 2Hartling, Lisa
- 2Johnson, David W.
- 2Klassen, Terry P.
- 2Patel, Hema
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2013-02-15
Klassen, Terry P., Plint, Amy C., Vandermeer, Ben, Tjosvold, Lisa, Hartling, Lisa, Fernandes, Ricardo M., Patel, Hema, Bialy, Liza M., Johnson, David W.
Background: Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. Objectives: To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. Search methods: We searched CENTRAL (2010, Issue 3) which contains the...
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From the trenches: a cross-sectional study applying the GRADE tool in systematic reviews of healthcare interventions.
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Dryden, D. M., Vandermeer, B., Seida, J., Hartling, L., Fernandes, R. M.
Background GRADE was developed to address shortcomings of tools to rate the quality of a body of evidence. While much has been published about GRADE, there are few empirical and systematic evaluations. Objective To assess GRADE for systematic reviews (SRs) in terms of inter-rater agreement and...
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2013-02-15
Tjosvold, Lisa, Klassen, Terry P., Bialy, Liza M., Hartling, Lisa, Vandermeer, Ben, Johnson, David W., Patel, Hema, Plint, Amy C., Fernandes, Ricardo M.
BACKGROUND: Previous systematic reviews have not shown clear benefit of glucocorticoids for acute viral bronchiolitis, but their use remains considerable. Recent large trials add substantially to current evidence and suggest novel glucocorticoid-including treatment approaches. OBJECTIVES: To...