This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
Theses and Dissertations
This collection contains theses and dissertations of graduate students of the University of Alberta. The collection contains a very large number of theses electronically available that were granted from 1947 to 2009, 90% of theses granted from 2009-2014, and 100% of theses granted from April 2014 to the present (as long as the theses are not under temporary embargo by agreement with the Faculty of Graduate and Postdoctoral Studies). IMPORTANT NOTE: To conduct a comprehensive search of all UofA theses granted and in University of Alberta Libraries collections, search the library catalogue at www.library.ualberta.ca - you may search by Author, Title, Keyword, or search by Department.
To retrieve all theses and dissertations associated with a specific department from the library catalogue, choose 'Advanced' and keyword search "university of alberta dept of english" OR "university of alberta department of english" (for example). Past graduates who wish to have their thesis or dissertation added to this collection can contact us at erahelp@ualberta.ca.
Items in this Collection
-
16R-HETE and 16S-HETE Alter Human Cytochrome P450 1B1 through Transcriptional and Allosteric Mechanism
DownloadFall 2022
Cardiac hypertrophy is a complex anomaly of the heart associated with increased muscle mass and thickening of the cell walls in response to accumulative stress. Although this condition occurs naturally, the prolonged state will progress into heart failure or even cause death. Recent studies have...
-
Cardioprotective effects of n-3 and n-6 PUFA derived epoxylipids against age-related cardiac alterations
DownloadSpring 2021
Age-associated changes leading to a decline in cardiac structure and function contribute to the increased susceptibility and incidence of cardiovascular diseases (CVD) in elderly individuals. A steady decline in mitochondrial function is recognized as an important biological consequence found in...
-
Fall 2012
Dioxins are widespread environmental contaminants that have been linked to a variety of deleterious effects on human health including increased cancer rates via aryl hydrocarbon receptor (AhR)-dependent mechanism. AhR is a transcription factor that regulates the expression of the...
-
MODULATING CYTOCHROME P450-MEDIATED ARACHIDONIC ACID METABOLISM AS A POTENTIAL NEW TREATMENT MODALITY FOR CARDIAC HYPERTROPHY
DownloadSpring 2017
El-Sherbeni, Ahmed Abd El-Hakeem
Arachidonic acid (AA) metabolism has long been a very appealing target for drug discovery and development efforts. Beside cyclooxygenase and lipoxygenase pathways, AA is also metabolized by the recently recognized cytochrome P450 (P450) pathway, forming several biologically-active...
-
MODULATION OF ARYL HYDROCARBON RECEPTOR (AHR)-REGULATED XENOBIOTIC METABOLIZING ENZYMES BY ARSENITE
DownloadFall 2013
Anwar-Mohamed, Anwar Gamal Abd El-Naser
Aryl hydrocarbon receptor (AhR) ligands and heavy metals are environmental co-contaminants and their molecular interaction may disrupt the coordinated regulation of AhR-dependent phase I and II drug metabolizing enzymes. As such, the effect of the heavy metal, As(III), on the AhR-regulated genes...
-
Fall 2022
Background: Pharmacogenomics (PGx) has potential to improve healthcare through personalized drug selection and dosing using genetic predictors of pharmacokinetics and/or pharmacodynamics (PK/PD). Research is uncovering PGx’s impact on morbidity and mortality from medication adverse effects and/or...