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- 10Wilman, Alan (Biomedical Engineering)
- 1De Zanche, Nicola (Oncology)
- 1Emery, Derek (Radiology and Diagnostic Imaging)
- 1Le, Lawrence H (Radiology and Diagnostic Imaging)
- 1Paterson, Ian (Division of Cardiology)
- 1Sacchi, Mauricio D (Physics)
- 1Chhetri, Gitanjali
- 1Chow, Kelvin
- 1Elkady, Ahmed
- 1Lagore, Russell Luke
- 1Lebel, Robert
- 1Nima Mehdizadeh
Magnetic resonance imaging is an essential tool for assessing soft tissues. The desire for increased signal-to-noise and improved tissue contrast has spurred development of imaging systems operating at magnetic fields exceeding 3.0 Tesla (T). Unfortunately, traditional imaging methods are of...
Development and Application of Quantitative Gradient-Echo MRI Techniques for Assessment of Iron and Myelin in the Multiple Sclerosis BrainDownload
Multiple Sclerosis (MS) is a progressive autoimmune and neurodegenerative disease of the Central Nervous System that results in demyelination and neuronal/axonal loss. Along with clinical evaluation, Magnetic Resonance Imaging (MRI) is the gold standard modality for diagnosing and monitoring MS,...
Magnetic resonance imaging (MRI) is a valuable imaging modality and is commonplace in diagnosing, evaluating, and understanding the pathobiology of many neurological disorders. Current methods are helpful in the diagnosis of multiple sclerosis (MS) but fail to provide useful longitudinal...
Diffuse myocardial fibrosis and other remodeling of the extracellular volume (ECV) in the heart are common pathological features in a variety of cardiac diseases. These microscopic alterations can be imaged non-invasively via changes in the spin-lattice (T1) relaxation time in magnetic resonance...
The popularity of magnetic resonance imaging (MRI) owes much to its flexibility. Sensitive to a host of different biophysical phenomena, parameters of the scan can be fine-tuned to highlight specific pathologies. One such mechanism for generating image contrast is magnetic susceptibility—the...
Transverse relaxation (T2)-weighted images are routinely acquired in clinics. However, T2 quantification is rarely performed as most of the specialized pulse sequences used to quantify T2 are time consuming and thus generally not used in a clinical setup. Nevertheless, there is strong interest in...
Tracking myelination and demyelination in the brain is a crucial part of studies on neurodegenerative diseases such as Multiple Sclerosis (MS). Classic MRI techniques are unable to provide enough information about the pathology of tracts and lesions. Multi-component analysis of multi-echo data...
Preamplifier Noise Figure Measurement and Radio Frequency Field Optimization in High Field Magnetic Resonance ImagingDownload
High field magnetic resonance imaging (MRI) is an area of research interest due to the associated improvement in image quality possible. This improvement comes at a cost. Hardware design becomes more complex in order to overcome technical challenges at these higher field strengths....
Quantitative susceptibility mapping (QSM) is an emerging magnetic resonance imaging (MRI) post-processing technique that uses phase images from a gradient echo sequence to create magnetic susceptibility maps. QSM is sensitive to paramagnetic iron found in various states of blood, from...
Osteoporosis is a bone disease characterized by the degradation of mechanical competence and support of the skeleton, leading to fracture risk of the wrist, vertebrae, and hip. The disease is due to major decrease of mass and deterioration of micro-structure of bone tissues. In this study, bone...