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Carbohydrate and Phosphorylcholine based Polymers Prepared by Reversible Addition-Fragmentation Chain Transfer Polymerization for Gene TherapyDownload
The study provides a comprehensive account on the development of novel synthetic carbohydrate and phosphorylcholine polymer based gene delivery vectors. Since the development and use of first non-viral vector for gene delivery applications, a wide range of polymers have been synthesized and...
Cryptosporidium, a waterborne protozoan pathogen that can cause gastrointestinal illness, is often found in surface waters that are used to supply drinking water. Filtration is a major barrier against Cryptosporidium in drinking water treatment processes. However, interactions between oocysts and...
Prebiotic-Chemistry Inspired Polymeric Coatings for the Surface Modification of Hydrophobic Polyethersulfone membranes for the Enhancement of their Antifouling and Antibacterial PropertiesDownload
Polyethersulfone (PES) membranes are very commonly used for wastewater treatment because of their excellent mechanical, chemical and thermal properties. However, the major concern associated with these membranes is their susceptibility to fouling due to their intrinsic hydrophobicity. Therefore,...
Synthesis and Characterization of Phosphorylcholine-based Polymers and Nanogels via the Reversible Addition Fragmentation Chain Transfer ProcessDownload
2-Methacryloyloxyethyl Phosphorylcholine is an interesting biocompatible monomer. An improved method for the synthesis of poly(MPC) and its copolymers using Reversible Addition-Fragmentation chain Transfer (RAFT) has been discussed in the first part of the thesis. Previous reports related to the...
Advances in polymer science and nanotechnology have allowed the development of biomaterials for cell-based applications, such as the delivery of a variety of drugs and genes, as well as supporting technologies, such as stem cell therapies, tissue engineering and cryopreservation. The progress in...