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- 7Fedorak, Richard (Medicine)
- 2Kroeker, Karen (Medicine)
- 2Madsen, Karen (Medicine)
- 1Goodman, Karen (Medicine)
- 1Greiner, Russ (Computer Science)
- 1Halloran, Brendan (Medicine)
- 1Beilman, Candace L
- 1Huang, Vivian Wai-Mei
- 1Kroeker, Karen I
- 1Lee, Thomas Wei Te
- 1Reich, Krista, M
- 1Tso, Robert
- 4Inflammatory bowel disease
- 2Crohn's disease
- 2Inflammatory Bowel Disease
Anti-TNF therapy is effective for the induction and maintenance of remission in patients with inflammatory bowel disease (IBD). The benefits of anti-TNF therapy include improved quality of life, steroid discontinuation, and reduced hospitalization and surgery rates. Due to their high costs and...
Environmental Exposures, Gut Microbiota, and Urinary Metabolomic Fingerprint of Crohn’s Disease Patients Who Have Undergone Ileo-colonic ResectionDownload
Inflammatory bowel disease (IBD) is an idiopathic disease that causes intestinal inflammation and lesions. Canada has one of the highest rates of IBD in the world. One of the major types of IBD is Crohn’s Disease (CD) and a large portion of CD patients will undergo surgical resection in the...
Nuclear Magnetic Resonance metabolomic fingerprint of the Interleukin 10 gene deficient mouse model of Inflammatory Bowel DiseaseDownload
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder that occurs as a consequence of a genetic mutation that results in an overly aggressive immune response to normal bacteria. Metabolomics is a new born cousin to genomics and proteomics and involves a high throughput...
Reproductive Knowledge Specific to Inflammatory Bowel Disease Among Women with IBD and Physicians who Treat Women with IBDDownload
BACKGROUND: Inflammatory Bowel Disease (IBD) affects women in their reproductive years. Women with IBD often choose not to have children, and this voluntary childlessness may be due to their concerns regarding the adverse effects of their IBD and its treatment on fertility, pregnancy, and the...
THE PSYCHOSOCIAL FUNCTIONING OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN EARLY ADULTHOOD IS IMPAIREDDownload
Inflammatory bowel disease is a chronic disease that is often diagnosed in childhood and adolescence. The objective of this study was to assess the impact of a diagnosis of IBD on the psychosocial functioning in early adulthood. This was a questionnaire-based cross-sectional study comparing...
The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel DiseaseDownload
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...
The influence of iron therapy on the clinical outcomes, the colonic bacteria microbiome and the urinary metabolomics in iron deficient subjectsDownload
Iron deficiency is a common problem facing subjects with inflammatory bowel disease and it is of recurrent nature. It is associated with lethargy, fatigue and poorer cognition independent of anaemia. These symptoms could be reversed with iron supplementation either via oral or intravenous route....