This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
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Fall 2021
Ducks, as the natural reservoir host of influenza A virus (IAV), do not exhibit the same detrimental symptoms when infected by IAV as other susceptible host species, such as chickens and humans. A dysregulated NLRP3 inflammasome response activated by IAV has been linked to severe host outcomes,...
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Colorectal Cancer Small Extracellular Vesicles Induce Matrix Metalloproteinase Expression, an Invasion-Promoting Phenotype, and CD147-Dependent MAPK/AP-1 Activation in Macrophages
DownloadFall 2020
Exosomes and small microvesicles are types of small extracellular vesicle (sEVs) secreted by cancerous and normal cells. sEVs are filled with cargo from cancer cells that may affect both nearby and distant tissues. sEVs from colorectal cancers that enter blood vessels draining the intestine will...
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Fall 2020
Influenza A viruses are a major cause of human and animal disease worldwide. Periodically, avian influenza A viruses from wild waterfowl, like ducks, pass through intermediate agricultural hosts and emerge into the human population as zoonotic diseases with high mortality rates and pandemic...
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Fall 2021
Valvular heart disease (VHD) is a common diagnosis with an approximate prevalence of 2.5% of the total population having moderate to severe VHD [1, 2]. The most common treatment for end-stage VHD is surgical valve replacement with constructs categorized into three classes: mechanical valves,...
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Fall 2023
Obesity is a worldwide epidemic that is associated with immune dysfunction. In human and rodent models, obesity-induced immune dysfunction has been characterized by lower T cell proliferation and interleukin (IL)-2 production. While the mechanisms responsible for the observed reduction in T cell...