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- 2Vascular endothelial growth factor
- 1Angiogenesis regulators
- 1Breast Cancer
Platelets, in addition to maintaining hemostasis, also stimulate angiogenesis by generating and releasing, upon activation, factors that promote the growth of new blood vessels. To date, at least 20 angiogenesis-regulating factors have been identified in platelets, including both promoters and...
Regulation of collagen type I production by ionizing radiation and transforming growth factor-β1 in primary human skin fibroblasts derived from early stage breast cancer patients in relation to acute radiation-induced toxicityDownload
Regulation of collagen type I (CI) in fibroblasts is critical for the onset and development of skin toxicities induced by radiation therapy (RT). Transforming growth factor beta-1 (TGF-β1) and vascular endothelial growth factor (VEGF) promote CI synthesis, while its degradation is modulated by...