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- 1ATP-sensitive potassium channel
- 1Acute coronary syndrome
- 1Binding affinity
- 1Bradford Hill considerations
- 1Heart disease
Building Evidence to Assess a Drug Safety Signal: the Association between Sulfonylureas and Adverse Cardiovascular EventsDownload
All drugs have the potential to cause adverse events that can result in hospitalization or death. In order to protect the public health, it is critical to employ methods to detect and assess adverse drug events in a timely manner. One of the most controversial and long standing drug safety issue...
The cardiac sodium-calcium exchanger (NCX) is an important membrane protein which regulates cellular calcium necessary for the optimal contractile function of the heart. NCX has become a focal point in ischemic heart disease (IHD) research as evidence suggests that reactive oxygen species (ROS)...