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- 1Cell-mediated cytotoxicity
- 1E. coli O157:H7
- 2Chemistry, Department of
- 1Helmholtz-Alberta Initiative
- 1Helmholtz-Alberta Initiative/Journal Articles & Research Abstracts (Helmholtz-Alberta Initiative)
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 1Chemistry, Department of/Journal Articles (Chemistry)
Impact of the nature and size of the polymeric backbone on the ability of heterobifunctional ligands to mediate Shiga toxin and serum amyloid P component ternary complex formation.Download
Inhibition of AB(5)-type bacterial toxins can be achieved by heterobifunctional ligands (BAITs) that mediate assembly of supramolecular complexes involving the toxin's pentameric cell membrane-binding subunit and an endogenous protein, serum amyloid P component, of the innate immune system....
Na+/H+ exchange activity during phagocytosis in human neutrophils: Role of Fc7 receptors and tyrosine kinasesDownload
Abstract. In neutrophils, binding and phagocytosis facilitate subsequent intracellular killing of microorganisms. Activity of Na+/H ÷ exchangers (NHEs) participates in these events, especially in regulation of intracellular pH (pHi) by compensating for the H ÷ load generated by the respiratory...
Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation
Lipids from mycobacteria can be presented to human T cells by group 1 CD1 Ag-presenting molecules (CD1a, CD1b, and CD1c). Group 1 CD1-restricted T cells are activated by lipid Ags presented by myeloid dendritic cells (DCs), after which they generate antibacterial effector functions, including...
Transcriptional responses of the brain-gonad-liver axis of fathead minnows exposed to untreated and ozone-treated oil sands process-affected water