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- 1Adrenomedullin--Physiological effect
- 1Animal Model
- 1Endothelial colony forming cells
- 1Endothelial progenitor cells
- 1Human placenta
Existence of endothelial progenitor cells with self-renewal and clonogenic potential in normal human placenta and preeclampsiaDownload
Preeclampsia (PE) is the leading cause of maternal death in developing countries. PE is defined as hypertension and proteinuria after 20 weeks of gestation. The only curative treatment is placental delivery. Evidence suggests that placental vasculature is disturbed with shallow invasion of...
Preeclampsia, defined as new-onset hypertension after 20 weeks of gestation with concurrent proteinuria, is the leading cause of maternal mortality. Preeclampsia is a multi-system disorder with serious maternal and fetal morbidities, which affects 2 – 8% of pregnancies worldwide. Although the...
The Role of Matrix Metalloproteinase-2 in the Pathophysiology of a Reduced Utero-Placental Perfusion Pressure Model of PreeclampsiaDownload
Preeclampsia is a leading cause of maternal and fetal morbidity/mortality and induced preterm birth. Endothelin-1 (ET-1) is a potent vasoactive agent, shown to be involved in the vascular endothelial dysfunction of preeclampsia. Big endothelin (bigET) is cleaved to ET-1 by several enzymes...