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- 1Alberta Centre for Child, Family and Community Research
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- 1Benson, Curtis A
- 1Berry, R
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Can caffeine alter blood potassium concentration or the perception of pain and fatigue after a 1 km cycling sprint?Download
Caffeine is used by some athletes to improve endurance performance, however, the mechanism(s) by which caffeine elicits performance improvements have been unclear. The purpose of this study was to investigate the effects of caffeine on pain perception, fatigue perception, plasma catecholamine...
Central nervous system plasticity associated with pain in a mouse model of multiple sclerosis, and the antinociceptive effects of the antidepressant phenelzineDownload
Multiple sclerosis (MS) is a chronic, progressive disease that involves neuroinflammation, demyelination, and neurodegeneration within the central nervous system (CNS). While loss of motor function and paralysis are considered the primary clinical consequences of MS, the disease is also...
Neuropathic pain afflicts 1.5-3% of the general population. It can be initiated by traumatic nerve injuries or diseases such as diabetic or post-herpetic neuropathy. Neuropathic pain is often initiated by abnormal spontaneous activity in sensory neurons and this provokes increased excitability of...
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by neurodegeneration, inflammation and demyelination. Symptoms of multiple sclerosis not only include motor deficits, but also secondary symptoms of pain, depression and anxiety. The purpose of...
Instruments for Scoring Pain, Non-Pain Related Distress, Analgesia, and Sedation in Pediatric Mechanically Ventilated Patients and their Efficacy and Effectiveness in Practice: A Systematic ReviewDownload
Objective pain and sedation assessment scales to standardize measures of distress in mechanically ventilated pediatric patients are increasingly available, but few have been evaluated for efficacy and effectiveness in this population. The purpose of paper one was to identify and evaluate...
Investigating the Effects of N2-Acetylphenelzine in the Sexes in Experimental Autoimmune EncephalomyelitisDownload
Chronic pain is a highly prevalent symptom in Multiple Sclerosis (MS) and affects approximately half of patients at some stage of the disease. MS affects women more frequently than men and neuropathic pain is also reported as more severe, and frequent, in females with the disease. The underlying...