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Fall 2010
In many tumors, persistently-active signal transducer and activator of transcription 3 (STAT3) imparts several oncogenic features such as survival, proliferation, angiogenesis, and immune escape. Therefore, STAT3 targeting in cancer and cancer-exposed dendritic cells (DCs) is important for cancer...
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Spring 2022
Small interfering ribonucleic acids (siRNA) effectively downregulate the specific gene expression from cleaving the associated messenger RNA (mRNA) in the cytoplasm, which is a promising strategy in cancer management as one of the origins of cancer is the unregulated expression of the oncogene....