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Skip to Search Results- 11Graduate Studies and Research, Faculty of
- 11Graduate Studies and Research, Faculty of/Theses and Dissertations
- 6Chemistry, Department of
- 6Chemistry, Department of/Journal Articles (Chemistry)
- 2Biological Sciences, Department of
- 2Biological Sciences, Department of/Journal Articles (Biological Sciences)
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An NMR-based approach to the structural and functional investigation of the Na+/H+ exchanger NHE1
DownloadFall 2013
The Na+/H+ exchanger isoform 1 (NHE1) is the predominant isoform in mammalian cells, and regulates intracellular pH and ion concentrations. NHE1 also interacts with numerous proteins and signalling pathways. Consequently, it has been found to influence cell volume, growth, differentiation, and...
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2020-01-01
Hooper, R.W., Klein, B.A., Michaelis, V.K.
The design of new materials requires a deep understanding of the intricacies underpinning their structure–property relationships. These relationships are modified through synthesis and processing to create materials with new properties and characteristics to achieve a wide range of applications....
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2019-01-01
Ha, M., Thiessen, A.N., Sergeyev, I.V., Veinot, J.G.C., Michaelis, V.K.
Silicon nanoparticles (SiNPs) are intriguing materials and their properties fascinate the broader scientific community; they are also attractive to the biological and materials science sub-disciplines because of their established biological and environmental compatibility, as well as their...
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Exploration of Microscopic Structure and Dynamics in Halide Perovskite and Perovskite−Inspired Materials with Solid-State NMR Spectroscopy
DownloadSpring 2022
The work presented in this thesis describes the synthesis, structure, and optical properties of three different classes of halide-based perovskite materials, namely, metal halide perovskites of ABX3 type, halide double perovskites of A2B'B"X6 type, and “vacancy-ordered perovskites” of A2BX6 type...
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2017-05-04
Dynamic nuclear polarization (DNP) NMR spectroscopy, a high-polarization method, is rapidly changing the landscape of what is possible in solid-state nuclear magnetic resonance spectroscopy. To date, there have been over 200 publications discussing high-frequency DNP NMR of solids with more than...
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High-Frequency Dynamic Nuclear Polarization NMR for Solids: Part 2 – Development and Applications
Download2017-01-01
High-frequency dynamic nuclear polarization nuclear magnetic resonance (DNP NMR) spectroscopy is having a major impact on the far-reaching abilities of solid-state NMR. This high-sensitivity technique made possible by transferring high polarization from an unpaired electron source to an...
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2019-01-01
Bernard, G.M., Michaelis, V.K.
High‐field dynamic nuclear polarization nuclear magnetic resonance (DNP NMR) spectroscopy is rapidly emerging as a revolutionary analytical structural method by greatly enhancing the sensitivity of nuclear magnetic resonance. Innovative solutions are constantly being introduced to address the...
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J-Coupling Effects on Quantification of the 1.3 ppm Lipid Methylene Resonance with In-Vivo Magnetic Resonance Spectroscopy at 3 T
DownloadFall 2015
Quantification of 1.3 ppm lipid methylene protons by proton magnetic resonance spectroscopy has been shown to be relevant to a number of diseases. Additionally, T2 estimation of 1.3 ppm methylene protons has been used to grade the metastatic potential of colon tumours. J-coupling...
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Lead‐207 NMR spectroscopy at 1.4 T: Application of benchtop instrumentation to a challenging I = ½ nucleus
Download2020-01-01
Bernard, G.M., Michaelis, V.K.
The practicality of obtaining liquid‐ and solid‐state 207Pb nuclear magnetic resonance (NMR) spectra with a low permanent‐field magnet is investigated. Obtaining 207Pb NMR spectra of salts in solution is shown to be viable for samples as dilute as 0.05 M. The concentration dependence of the 207Pb...